3JVH

Crystal structure of 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with FOL fragment 8395

Summary for 3JVH

Entry DOI	10.2210/pdb3jvh/pdb
Related	3F0E 3F0G 3IEQ 3IEW 3IKE 3IKF
Descriptor	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, 5-[(pyridin-3-ylmethyl)amino]-1H-pyrazole-4-carboxamide, ... (5 entities in total)
Functional Keywords	niaid, ssgcid, seattle dtructural genomics center for infectious disease, fragment crystallography, fragments of life, zinc-binding fragment, isoprene biosynthesis, lyase, metal-binding, structural genomics, seattle structural genomics center for infectious disease
Biological source	Burkholderia pseudomallei (Pseudomonas pseudomallei)
Total number of polymer chains	3
Total formula weight	59401.33
Authors	Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2009-09-16, release date: 2009-09-29, Last modification date: 2023-09-06)
Primary citation	Begley, D.W.,Hartley, R.C.,Davies, D.R.,Edwards, T.E.,Leonard, J.T.,Abendroth, J.,Burris, C.A.,Bhandari, J.,Myler, P.J.,Staker, B.L.,Stewart, L.J. Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12:63-76, 2011 Cited by PubMed: 21359640 DOI: 10.1007/s10969-011-9102-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.69 Å)

Structure validation