8DQ7

The structure of NicA2 variant F104L/A107T/S146I/G317D/H368R/L449V/N462S from Pseudomonas putida

Summary for 8DQ7

• Entry DOI: 10.2210/pdb8dq7/pdb
• Descriptor: Amine oxidase, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE (3 entities in total)
• Functional Keywords: nicotine-degrading enzyme, flavoprotein
• Biological source: Pseudomonas putida S16
• Total number of polymer chains: 2
• Total formula weight: 96926.84

Authors

Wu, K.,Dulchavsky, M.,Li, J.,Bardwell, J.C.A. (deposition date: 2022-07-18, release date: 2023-07-26, Last modification date: 2023-10-18)

• Primary citation: Dulchavsky, M.,Mitra, R.,Wu, K.,Li, J.,Boer, K.,Liu, X.,Zhang, Z.,Vasquez, C.,Clark, C.T.,Funckes, K.,Shankar, K.,Bonnet-Zahedi, S.,Siddiq, M.,Sepulveda, Y.,Suhandynata, R.T.,Momper, J.D.,Calabrese, A.N.,George, O.,Stull, F.,Bardwell, J.C.A.; Directed evolution unlocks oxygen reactivity for a nicotine-degrading flavoenzyme.; Nat.Chem.Biol., 2023; PubMed: 37770699; DOI: 10.1038/s41589-023-01426-y

Experimental method

X-RAY DIFFRACTION (2.1 Å)