8DQ8
The structure of NicA2 variant F104L/A107T/S146I/G317D/H368R/L449V/N462S in complex with N-methylmyosmine
Summary for 8DQ8
Entry DOI | 10.2210/pdb8dq8/pdb |
Descriptor | Amine oxidase, (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, ... (5 entities in total) |
Functional Keywords | nicotine-degrading enzyme, flavoprotein |
Biological source | Pseudomonas putida S16 |
Total number of polymer chains | 2 |
Total formula weight | 97375.44 |
Authors | Wu, K.,Dulchavsky, M.,Li, J.,Bardwell, J.C.A. (deposition date: 2022-07-18, release date: 2023-07-26, Last modification date: 2023-11-08) |
Primary citation | Dulchavsky, M.,Mitra, R.,Wu, K.,Li, J.,Boer, K.,Liu, X.,Zhang, Z.,Vasquez, C.,Clark, C.T.,Funckes, K.,Shankar, K.,Bonnet-Zahedi, S.,Siddiq, M.,Sepulveda, Y.,Suhandynata, R.T.,Momper, J.D.,Calabrese, A.N.,George, O.,Stull, F.,Bardwell, J.C.A. Directed evolution unlocks oxygen reactivity for a nicotine-degrading flavoenzyme. Nat.Chem.Biol., 19:1406-1414, 2023 Cited by PubMed: 37770699DOI: 10.1038/s41589-023-01426-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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