8DQ8
The structure of NicA2 variant F104L/A107T/S146I/G317D/H368R/L449V/N462S in complex with N-methylmyosmine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Amine oxidase | polymer | 432 | 47675.9 | 2 | UniProt (F8G0P2) Pfam (PF01593) | Pseudomonas putida S16 | |
| 2 | C, F (A, B) | (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE | non-polymer | 162.2 | 2 | Chemie (NCT) | |||
| 3 | D, G (A, B) | DIHYDROFLAVINE-ADENINE DINUCLEOTIDE | non-polymer | 787.6 | 2 | Chemie (FDA) | |||
| 4 | E, H (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 603 | Chemie (HOH) |
Sequence modifications
A, B: 51 - 482 (UniProt: F8G0P2)
| PDB | External Database | Details |
|---|---|---|
| Leu 104 | Phe 104 | engineered mutation |
| Thr 107 | Ala 107 | engineered mutation |
| Ile 146 | Ser 146 | engineered mutation |
| Asp 317 | Gly 317 | engineered mutation |
| Arg 368 | His 368 | engineered mutation |
| Val 449 | Leu 449 | engineered mutation |
| Ser 462 | Asn 462 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 95351.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2023.7 | |
| All* | Total formula weight | 97375.4 |
