7TXD
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![BU of 7txd by Molmil](/molmil-images/mine/7txd) | Cryo-EM structure of BG505 SOSIP HIV-1 Env trimer in complex with CD4 receptor (D1D2) and broadly neutralizing darpin bnD.9 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Broadly neutralizing darpin bnd.9, ... | 著者 | Cerutti, G, Gorman, J, Kwong, P.D, Shapiro, L. | 登録日 | 2022-02-08 | 公開日 | 2023-04-12 | 最終更新日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | 主引用文献 | Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization. Nat.Struct.Mol.Biol., 30, 2023
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6VS5
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![BU of 6vs5 by Molmil](/molmil-images/mine/6vs5) | Mycobacterium tuberculosis dihydrofolate reductase in complex with 5-methyl-1-phenyl-1H-pyrazole-4-carboxylic acid (fragment 1) | 分子名称: | 5-methyl-1-phenyl-pyrazole-4-carboxylic acid, COBALT (II) ION, Dihydrofolate reductase, ... | 著者 | Ribeiro, J.A, Tyrakis, P, Blundell, T, Dias, M.V.B. | 登録日 | 2020-02-10 | 公開日 | 2020-07-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.758 Å) | 主引用文献 | Using a Fragment-Based Approach to Identify Alternative Chemical Scaffolds Targeting Dihydrofolate Reductase fromMycobacterium tuberculosis. Acs Infect Dis., 6, 2020
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8EEU
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![BU of 8eeu by Molmil](/molmil-images/mine/8eeu) | Venezuelan equine encephalitis virus-like particle in complex with Fab SKT05 | 分子名称: | Coat protein, Fab SKT05 heavy chain, Fab SKT05 light chain | 著者 | Tsybovsky, Y, Pletnev, S, Verardi, R, Roederer, M, Kwong, P.D. | 登録日 | 2022-09-07 | 公開日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses. Cell, 186, 2023
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8EEV
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![BU of 8eev by Molmil](/molmil-images/mine/8eev) | Venezuelan equine encephalitis virus-like particle in complex with Fab SKT-20 | 分子名称: | Coat protein, Fab SKT20 heavy chain, Fab SKT20 light chain | 著者 | Tsybovsky, Y, Pletnev, S, Verardi, R, Roederer, M, Kwong, P.D. | 登録日 | 2022-09-07 | 公開日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses. Cell, 186, 2023
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4N1T
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![BU of 4n1t by Molmil](/molmil-images/mine/4n1t) | Structure of human MTH1 in complex with TH287 | 分子名称: | 6-(2,3-dichlorophenyl)-N~4~-methylpyrimidine-2,4-diamine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION | 著者 | Berntsson, R.P.-A, Jemth, A, Gustafsson, R, Svensson, L.M, Helleday, T, Stenmark, P. | 登録日 | 2013-10-04 | 公開日 | 2014-04-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool. Nature, 508, 2014
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4N1U
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![BU of 4n1u by Molmil](/molmil-images/mine/4n1u) | Structure of human MTH1 in complex with TH588 | 分子名称: | 7,8-dihydro-8-oxoguanine triphosphatase, N~4~-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine, SULFATE ION | 著者 | Berntsson, R.P.-A, Jemth, A, Gustafsson, R, Svensson, L.M, Helleday, T, Stenmark, P. | 登録日 | 2013-10-04 | 公開日 | 2014-04-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool. Nature, 508, 2014
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7MY2
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![BU of 7my2 by Molmil](/molmil-images/mine/7my2) | |
7MY3
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![BU of 7my3 by Molmil](/molmil-images/mine/7my3) | |
1BBX
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![BU of 1bbx by Molmil](/molmil-images/mine/1bbx) | NON-SPECIFIC PROTEIN-DNA INTERACTIONS IN THE SSO7D-DNA COMPLEX, NMR, 1 STRUCTURE | 分子名称: | DNA (5'-D(*CP*TP*AP*GP*CP*GP*CP*GP*CP*TP*AP*G)-3'), DNA-BINDING PROTEIN 7D | 著者 | Agback, P, Baumann, H, Knapp, S, Ladenstein, R, Hard, T. | 登録日 | 1998-04-24 | 公開日 | 1998-10-14 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Architecture of Nonspecific Protein-DNA Interactions in the Sso7D-DNA Complex Nat.Struct.Biol., 5, 1998
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7Z7C
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![BU of 7z7c by Molmil](/molmil-images/mine/7z7c) | |
8ELI
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![BU of 8eli by Molmil](/molmil-images/mine/8eli) | |
8EUW
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![BU of 8euw by Molmil](/molmil-images/mine/8euw) | |
8EUV
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![BU of 8euv by Molmil](/molmil-images/mine/8euv) | |
8EUU
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![BU of 8euu by Molmil](/molmil-images/mine/8euu) | Cryo-EM structure of HIV-1 BG505 DS-SOSIP ENV trimer bound to VRC34.01 FAB | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | 著者 | Pletnev, S, Kwong, P. | 登録日 | 2022-10-19 | 公開日 | 2023-09-27 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site. Nat Commun, 14, 2023
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8FIS
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![BU of 8fis by Molmil](/molmil-images/mine/8fis) | |
5ER2
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![BU of 5er2 by Molmil](/molmil-images/mine/5er2) | High-resolution X-ray diffraction study of the complex between endothiapepsin and an oligopeptide inhibitor. the analysis of the inhibitor binding and description of the rigid body shift in the enzyme | 分子名称: | 6-ammonio-N-{[(2R,3R)-3-{[N-(tert-butoxycarbonyl)-L-phenylalanyl-3-(1H-imidazol-3-ium-4-yl)-L-alanyl]amino}-4-cyclohexyl-2-hydroxybutyl](2-methylpropyl)carbamoyl}-L-norleucyl-L-phenylalanine, ENDOTHIAPEPSIN | 著者 | Sali, A, Veerapandian, B, Cooper, J.B, Foundling, S.I, Hoover, D.J, Blundell, T.L. | 登録日 | 1991-01-02 | 公開日 | 1991-04-15 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | High-resolution X-ray diffraction study of the complex between endothiapepsin and an oligopeptide inhibitor: the analysis of the inhibitor binding and description of the rigid body shift in the enzyme. EMBO J., 8, 1989
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8F7Z
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![BU of 8f7z by Molmil](/molmil-images/mine/8f7z) | VRC34.01_mm28 bound to fusion peptide | 分子名称: | HIV-1 Env Fusion Peptide, VRC34_m228 Light Chain, VRC34_mm28 Heavy Chain | 著者 | Olia, A.S, Kwong, P.D. | 登録日 | 2022-11-21 | 公開日 | 2023-11-01 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site. Nat Commun, 14, 2023
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8AED
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![BU of 8aed by Molmil](/molmil-images/mine/8aed) | |
5ER1
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![BU of 5er1 by Molmil](/molmil-images/mine/5er1) | |
4WSB
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![BU of 4wsb by Molmil](/molmil-images/mine/4wsb) | Bat Influenza A polymerase with bound vRNA promoter | 分子名称: | Influenza A polymerase vRNA promoter 3' end, Influenza A polymerase vRNA promoter 5' end, PHOSPHATE ION, ... | 著者 | Cusack, S, Pflug, A, Guilligay, D, Reich, S. | 登録日 | 2014-10-26 | 公開日 | 2014-11-19 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structural insight into cap-snatching and RNA synthesis by influenza polymerase. Nature, 516, 2014
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4WRT
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![BU of 4wrt by Molmil](/molmil-images/mine/4wrt) | Crystal structure of Influenza B polymerase with bound vRNA promoter (form FluB2) | 分子名称: | Influenza virus polymerase vRNA promoter 3' end, Influenza virus polymerase vRNA promoter 5' end, PA, ... | 著者 | Reich, S, Guilligay, D, Pflug, A, Cusack, S. | 登録日 | 2014-10-25 | 公開日 | 2014-11-19 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural insight into cap-snatching and RNA synthesis by influenza polymerase. Nature, 516, 2014
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4WSA
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![BU of 4wsa by Molmil](/molmil-images/mine/4wsa) | Crystal structure of Influenza B polymerase bound to the vRNA promoter (FluB1 form) | 分子名称: | Influenza B vRNA promoter 3' end, Influenza B vRNA promoter 5' end, PA, ... | 著者 | Reich, S, Guilligay, D, Pflug, A, Cusack, S. | 登録日 | 2014-10-26 | 公開日 | 2014-11-19 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structural insight into cap-snatching and RNA synthesis by influenza polymerase. Nature, 516, 2014
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3ER3
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![BU of 3er3 by Molmil](/molmil-images/mine/3er3) | The active site of aspartic proteinases | 分子名称: | 6-ammonio-N-[(2R,4R,5R)-5-{[N-(tert-butoxycarbonyl)-L-phenylalanyl-3-(1H-imidazol-3-ium-4-yl)-L-alanyl]amino}-6-cyclohexyl-4-hydroxy-2-(2-methylpropyl)hexanoyl]-L-norleucylphenylalanine, ENDOTHIAPEPSIN | 著者 | Al-Karadaghi, S, Cooper, J.B, Veerapandian, B, Hoover, D, Blundell, T.L. | 登録日 | 1991-01-02 | 公開日 | 1991-04-15 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Active Site of Aspartic Proteinases FEBS Lett., 174, 1984
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8DEQ
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![BU of 8deq by Molmil](/molmil-images/mine/8deq) | Cryo-EM local refinement of antibody SKV09 in complex with VEEV alphavirus spike glycoprotein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SKV09 Fab Heavy Chain, SKV09 Fab Light Chain, ... | 著者 | Casner, R.G, Verardi, R, Roederer, M, Shapiro, L. | 登録日 | 2022-06-21 | 公開日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (6 Å) | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses. Cell, 186, 2023
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8DER
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![BU of 8der by Molmil](/molmil-images/mine/8der) | Cryo-EM local refinement of antibody SKV16 in complex with VEEV alphavirus spike glycoprotein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SKV16 Fab Heavy Chain, ... | 著者 | Casner, R.G, Verardi, R, Roederer, M, Shapiro, L. | 登録日 | 2022-06-21 | 公開日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses. Cell, 186, 2023
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