7Z7C
Broadly neutralizing DARPin bnD.8 in complex with the HIV-1 envelope variable loop 3 peptide V3 (BF520)
Summary for 7Z7C
Entry DOI | 10.2210/pdb7z7c/pdb |
Descriptor | Broadly neutralizing DARPin bnD.8, Envelope glycoprotein gp160, GLYCINE, ... (5 entities in total) |
Functional Keywords | darpin, hiv, de novo protein |
Biological source | synthetic construct More |
Total number of polymer chains | 2 |
Total formula weight | 19754.15 |
Authors | Mittl, P.R.,Gloegl, M. (deposition date: 2022-03-15, release date: 2023-03-29, Last modification date: 2024-02-07) |
Primary citation | Glogl, M.,Friedrich, N.,Cerutti, G.,Lemmin, T.,Kwon, Y.D.,Gorman, J.,Maliqi, L.,Mittl, P.R.E.,Hesselman, M.C.,Schmidt, D.,Weber, J.,Foulkes, C.,Dingens, A.S.,Bylund, T.,Olia, A.S.,Verardi, R.,Reinberg, T.,Baumann, N.S.,Rusert, P.,Dreier, B.,Shapiro, L.,Kwong, P.D.,Pluckthun, A.,Trkola, A. Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization. Nat.Struct.Mol.Biol., 30:1323-1336, 2023 Cited by PubMed: 37605043DOI: 10.1038/s41594-023-01062-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.22 Å) |
Structure validation
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