7Z7C

Broadly neutralizing DARPin bnD.8 in complex with the HIV-1 envelope variable loop 3 peptide V3 (BF520)

Summary for 7Z7C

Entry DOI	10.2210/pdb7z7c/pdb
Descriptor	Broadly neutralizing DARPin bnD.8, Envelope glycoprotein gp160, GLYCINE, ... (5 entities in total)
Functional Keywords	darpin, hiv, de novo protein
Biological source	synthetic construct More
Total number of polymer chains	2
Total formula weight	19754.15
Authors	Mittl, P.R.,Gloegl, M. (deposition date: 2022-03-15, release date: 2023-03-29, Last modification date: 2024-02-07)
Primary citation	Glogl, M.,Friedrich, N.,Cerutti, G.,Lemmin, T.,Kwon, Y.D.,Gorman, J.,Maliqi, L.,Mittl, P.R.E.,Hesselman, M.C.,Schmidt, D.,Weber, J.,Foulkes, C.,Dingens, A.S.,Bylund, T.,Olia, A.S.,Verardi, R.,Reinberg, T.,Baumann, N.S.,Rusert, P.,Dreier, B.,Shapiro, L.,Kwong, P.D.,Pluckthun, A.,Trkola, A. Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization. Nat.Struct.Mol.Biol., 30:1323-1336, 2023 Cited by PubMed: 37605043 DOI: 10.1038/s41594-023-01062-z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.22 Å)

Structure validation