4WRT

Crystal structure of Influenza B polymerase with bound vRNA promoter (form FluB2)

Summary for 4WRT

DescriptorInfluenza virus polymerase vRNA promoter 3' end, Influenza virus polymerase vRNA promoter 5' end, PA, ... (6 entities in total)
Functional Keywordstransferase-rna complex, transferase/rna
Biological sourceInfluenza B virus
Total number of polymer chains5
Total molecular weight273016.01
Authors
Reich, S.,Guilligay, D.,Pflug, A.,Cusack, S. (deposition date: 2014-10-25, release date: 2014-11-19, Last modification date: 2019-04-03)
Primary citation
Reich, S.,Guilligay, D.,Pflug, A.,Malet, H.,Berger, I.,Crepin, T.,Hart, D.,Lunardi, T.,Nanao, M.,Ruigrok, R.W.,Cusack, S.
Structural insight into cap-snatching and RNA synthesis by influenza polymerase.
Nature, 516:361-366, 2014
PubMed: 25409151 (PDB entries with the same primary citation)
DOI: 10.1038/nature14009
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone 0.2141 0.1% 1.5% 2.3% 0.61MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution