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7CMZ
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BU of 7cmz by Molmil
Crystal Structure of BRCT7/8 in Complex with the APS Motif of PHF8
分子名称: DNA topoisomerase 2-binding protein 1, Histone lysine demethylase PHF8, POTASSIUM ION, ...
著者Che, S.Y, Ma, S, Cao, C, Yao, Z, Shi, L, Yang, N.
登録日2020-07-29
公開日2021-03-17
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.695 Å)
主引用文献PHF8-promoted TOPBP1 demethylation drives ATR activation and preserves genome stability.
Sci Adv, 7, 2021
7YFG
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BU of 7yfg by Molmil
Structure of the Rat GluN1-GluN2C NMDA receptor in complex with glycine and glutamate (major class in asymmetry)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
著者Zhang, M, Zhang, J, Guo, F, Li, Y, Zhu, S.
登録日2022-07-08
公開日2023-03-29
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
Nat.Struct.Mol.Biol., 30, 2023
7YFM
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BU of 7yfm by Molmil
Structure of GluN1b-GluN2D NMDA receptor in complex with agonists glycine and glutamate.
分子名称: Glutamate receptor ionotropic, NMDA 2D, Isoform 6 of Glutamate receptor ionotropic, ...
著者Zhang, J.L, Zhu, S.J, Zhang, M.
登録日2022-07-08
公開日2023-03-29
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
Nat.Struct.Mol.Biol., 30, 2023
7YFH
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BU of 7yfh by Molmil
Structure of the Rat GluN1-GluN2C NMDA receptor in complex with glycine, glutamate and (R)-PYD-106
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
著者Zhang, M, Zhang, J, Guo, F, Li, Y, Zhu, S.
登録日2022-07-08
公開日2023-03-29
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
Nat.Struct.Mol.Biol., 30, 2023
7JN7
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BU of 7jn7 by Molmil
Human DPP9-CARD8 complex
分子名称: Caspase recruitment domain-containing protein 8, Dipeptidyl peptidase 9, [(2~{R})-1-[(2~{R})-2-azanyl-3-methyl-butanoyl]pyrrolidin-2-yl]boronic acid
著者Sharif, H, Hollingsworth, L.R.
登録日2020-08-04
公開日2021-05-19
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment.
Immunity, 54, 2021
7JKQ
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BU of 7jkq by Molmil
Human DPP9-CARD8 complex
分子名称: Caspase recruitment domain-containing protein 8, Dipeptidyl peptidase 9
著者Sharif, H, Hollingsworth, L.R.
登録日2020-07-28
公開日2021-05-26
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment.
Immunity, 54, 2021
7KRN
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BU of 7krn by Molmil
Structure of SARS-CoV-2 backtracked complex bound to nsp13 helicase - nsp13(1)-BTC
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ...
著者Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
登録日2020-11-20
公開日2021-04-21
最終更新日2025-05-14
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
7KRP
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BU of 7krp by Molmil
Structure of SARS-CoV-2 backtracked complex complex bound to nsp13 helicase - BTC (local refinement)
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHAPSO, MAGNESIUM ION, ...
著者Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
登録日2020-11-20
公開日2021-04-21
最終更新日2025-05-21
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
7KRO
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BU of 7kro by Molmil
Structure of SARS-CoV-2 backtracked complex complex bound to nsp13 helicase - nsp13(2)-BTC
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ...
著者Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
登録日2020-11-20
公開日2021-04-21
最終更新日2025-06-04
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MSJ
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BU of 7msj by Molmil
The crystal structure of mouse HVEM
分子名称: SULFATE ION, Tumor necrosis factor receptor superfamily member 14
著者Liu, W, Ramagopal, U, Garrett-Thompson, S.C, Fedorov, E, Bonanno, J.B, Almo, S.C.
登録日2021-05-11
公開日2021-10-27
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160.
J.Exp.Med., 218, 2021
7MSG
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BU of 7msg by Molmil
The crystal structure of LIGHT in complex with HVEM and CD160
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD160 antigen, soluble form,Tumor necrosis factor receptor superfamily member 14, ...
著者Liu, W, Ramagopal, U, Garrett-Thompson, S.C, Fedorov, E, Bonanno, J.B, Almo, S.C.
登録日2021-05-11
公開日2021-10-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160.
J.Exp.Med., 218, 2021
5GSV
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BU of 5gsv by Molmil
Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide 142-5
分子名称: 10-mer peptide from Spike protein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
著者Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F.
登録日2016-08-17
公開日2017-04-26
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.996 Å)
主引用文献Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.
J. Immunol., 198, 2017
5GR7
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BU of 5gr7 by Molmil
Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide 37-1
分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-D alpha chain, ...
著者Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F.
登録日2016-08-08
公開日2017-06-07
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.
J. Immunol., 198, 2017
5GSR
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BU of 5gsr by Molmil
Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide I5A
分子名称: 9-mer peptide from Spike protein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
著者Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F.
登録日2016-08-17
公開日2017-04-26
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.198 Å)
主引用文献Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.
J. Immunol., 198, 2017
4MOD
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BU of 4mod by Molmil
Structure of the MERS-CoV fusion core
分子名称: HR1 of S protein, LINKER, HR2 of S protein
著者Gao, J, Lu, G, Qi, J, Li, Y, Wu, Y, Deng, Y, Geng, H, Xiao, H, Tan, W, Yan, J, Gao, G.F.
登録日2013-09-12
公開日2013-10-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Structure of the fusion core and inhibition of fusion by a heptad repeat peptide derived from the S protein of Middle East respiratory syndrome coronavirus.
J.Virol., 87, 2013
5GY3
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BU of 5gy3 by Molmil
The crystal structure of endoglucanase Cel10, a family 8 glycosyl hydrolase from Klebsiella pneumoniae
分子名称: Glucanase
著者Attigani, A, Li, S.P, Sun, L.F.
登録日2016-09-21
公開日2016-12-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献The crystal structure of the endoglucanase Cel10, a family 8 glycosyl hydrolase from Klebsiella pneumoniae
Acta Crystallogr F Struct Biol Commun, 72, 2016
5GYQ
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BU of 5gyq by Molmil
Putative receptor-binding domain of bat-derived coronavirus HKU9 spike protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Huang, C, Qi, J, Gao, G.F.
登録日2016-09-23
公開日2016-10-26
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Putative Receptor Binding Domain of Bat-Derived Coronavirus HKU9 Spike Protein: Evolution of Betacoronavirus Receptor Binding Motifs
Biochemistry, 55, 2016
5GSB
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BU of 5gsb by Molmil
Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide 37-3
分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-D alpha chain, ...
著者Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F.
登録日2016-08-15
公開日2017-07-12
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.
J. Immunol., 198, 2017
5HFM
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BU of 5hfm by Molmil
Gp41-targeting HIV-1 fusion inhibitors with hook-like Ile-Asp-Leu tail
分子名称: Envelope glycoprotein gp160,gp41 CHR region, TRIS(HYDROXYETHYL)AMINOMETHANE
著者Zhu, Y, Ye, S, Zhang, R.
登録日2016-01-07
公開日2017-01-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.298 Å)
主引用文献Rational improvement of gp41-targeting HIV-1 fusion inhibitors: an innovatively designed Ile-Asp-Leu tail with alternative conformations
Sci Rep, 6, 2016
8BVD
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BU of 8bvd by Molmil
FimH lectin domain in complex with mannose C-linked to quinoline
分子名称: (2R,3S,4R,5S,6R)-2-(hydroxymethyl)-6-[(E)-3-quinolin-6-ylprop-2-enyl]oxane-3,4,5-triol, Type 1 fimbrin D-mannose specific adhesin
著者Bouckaert, J, Bridot, C.
登録日2022-12-03
公開日2023-02-15
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.995 Å)
主引用文献Insightful Improvement in the Design of Potent Uropathogenic E. coli FimH Antagonists.
Pharmaceutics, 15, 2023
5HFL
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BU of 5hfl by Molmil
Gp41-targeting HIV-1 fusion inhibitors with helical Ile-Asp-Leu tail
分子名称: Envelope glycoprotein,gp41 CHR region
著者Zhu, Y, Ye, S, Zhang, R.
登録日2016-01-07
公開日2017-01-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.294 Å)
主引用文献Rational improvement of gp41-targeting HIV-1 fusion inhibitors: an innovatively designed Ile-Asp-Leu tail with alternative conformations
Sci Rep, 6, 2016
8BXY
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BU of 8bxy by Molmil
FimH in complex with alpha1,6 core-fucosylated oligomannose-3, crystallized in the trigonal space group
分子名称: NICKEL (II) ION, SULFATE ION, Type 1 fimbrin D-mannose specific adhesin, ...
著者Bridot, C, Bouckaert, J, Krammer, E.-M.
登録日2022-12-11
公開日2023-04-12
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci- and high-mannose type N-glycan receptors.
J.Biol.Chem., 299, 2023
8BY3
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BU of 8by3 by Molmil
FimH lectin domain in complex with oligomannose-6
分子名称: NICKEL (II) ION, SULFATE ION, Type 1 fimbrin D-mannose specific adhesin, ...
著者Bouckaert, J, Bourenkov, G.P.
登録日2022-12-11
公開日2023-04-12
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.186 Å)
主引用文献Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci- and high-mannose type N-glycan receptors.
J.Biol.Chem., 299, 2023
3V7T
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BU of 3v7t by Molmil
Crystal Structure of Human Beta-Tryptase Complexed with a Synthetic Inhibitor with a Tropanylamide Scaffold
分子名称: CARBONATE ION, TPSB2 protein, {(3-exo)-3-[5-(aminomethyl)-2-fluorophenyl]-8-azabicyclo[3.2.1]oct-8-yl}(4-bromo-3-methyl-5-propoxythiophen-2-yl)methanone
著者Zhang, Y, Colonna, C, Michot, N.
登録日2011-12-22
公開日2012-03-14
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献A beta-tryptase inhibitor with a tropanylamide scaffold to improve in vitro stability and to lower hERG channel binding affinity
Bioorg.Med.Chem.Lett., 22, 2012
6DFI
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BU of 6dfi by Molmil
Crystal structure of anti-Zika antibody Z021 bound to Zika virus envelope protein DIII
分子名称: Zika virus envelope protein DIII, anti-Zika antibody Z021, Heavy Chain, ...
著者Keeffe, J.R, Bjorkman, P.J.
登録日2018-05-14
公開日2018-10-24
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates.
Cell Rep, 25, 2018

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件を2025-07-09に公開中

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