4MOD

Structure of the MERS-CoV fusion core

Summary for 4MOD

• Entry DOI: 10.2210/pdb4mod/pdb
• Related: 1WDF 1WNC
• Descriptor: HR1 of S protein, LINKER, HR2 of S protein (2 entities in total)
• Functional Keywords: mers-cov, viral envelope proteins, spike, trimer of hairpins, 6-helix bundle, membrane fusion, viral protein
• Biological source: Human betacoronavirus 2c EMC/2012 (MERS-CoV); More
• Total number of polymer chains: 2
• Total formula weight: 27805.08

Authors

Gao, J.,Lu, G.,Qi, J.,Li, Y.,Wu, Y.,Deng, Y.,Geng, H.,Xiao, H.,Tan, W.,Yan, J.,Gao, G.F. (deposition date: 2013-09-12, release date: 2013-10-09, Last modification date: 2023-11-08)

• Primary citation: Gao, J.,Lu, G.,Qi, J.,Li, Y.,Wu, Y.,Deng, Y.,Geng, H.,Li, H.,Wang, Q.,Xiao, H.,Tan, W.,Yan, J.,Gao, G.F.; Structure of the fusion core and inhibition of fusion by a heptad repeat peptide derived from the S protein of Middle East respiratory syndrome coronavirus.; J.Virol., 87:13134-13140, 2013; PubMed: 24067982; DOI: 10.1128/JVI.02433-13

Experimental method

X-RAY DIFFRACTION (1.901 Å)