4DEN
 
 | | Structural insightsinto potent, specific anti-HIV property of actinohivin; Crystal structure of actinohivin in complex with alpha(1-2) mannobiose moiety of high-mannose type glycan of gp120 | | 分子名称: | Actinohivin, POTASSIUM ION, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose | | 著者 | Hoque, M.M, Suzuki, K, Tsunoda, M, Jiang, J, Zhang, F, Takahashi, A, Naomi, O, Zhang, X, Sekiguchi, T, Tanaka, H, Omura, S, Takenaka, A. | | 登録日 | 2012-01-20 | | 公開日 | 2012-11-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural insights into the specific anti-HIV property of actinohivin: structure of its complex with the alpha(1–2)mannobiose moiety of gp120
Acta Crystallogr.,Sect.D, 68, 2012
|
|
3JA7
 | | Cryo-EM structure of the bacteriophage T4 portal protein assembly at near-atomic resolution | | 分子名称: | Portal protein gp20 | | 著者 | Sun, L, Zhang, X, Gao, S, Rao, P.A, Padilla-Sanchez, V, Chen, Z, Sun, S, Xiang, Y, Subramaniam, S, Rao, V.B, Rossmann, M.G. | | 登録日 | 2015-04-21 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM structure of the bacteriophage T4 portal protein assembly at near-atomic resolution.
Nat Commun, 6, 2015
|
|
1KHC
 | | Crystal Structure of the PWWP Domain of Mammalian DNA Methyltransferase Dnmt3b | | 分子名称: | DNA cytosine-5 methyltransferase 3B2, UNKNOWN ATOM OR ION | | 著者 | Qiu, C, Sawada, K, Zhang, X, Cheng, X. | | 登録日 | 2001-11-29 | | 公開日 | 2002-02-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds.
Nat.Struct.Biol., 9, 2002
|
|
2F0X
 | | Crystal structure and function of human thioesterase superfamily member 2(THEM2) | | 分子名称: | SULFATE ION, Thioesterase superfamily member 2 | | 著者 | Cheng, Z, Song, F, Shan, X, Wang, Y, Wei, Z, Gong, W. | | 登録日 | 2005-11-14 | | 公開日 | 2006-10-10 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of human thioesterase superfamily member 2
Biochem.Biophys.Res.Commun., 349, 2006
|
|
1S3S
 | | Crystal structure of AAA ATPase p97/VCP ND1 in complex with p47 C | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin containing protein) (VCP) [Contains: Valosin], p47 protein | | 著者 | Dreveny, I, Kondo, H, Uchiyama, K, Shaw, A, Zhang, X, Freemont, P.S. | | 登録日 | 2004-01-14 | | 公開日 | 2004-03-30 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47.
Embo J., 23, 2004
|
|
3LQ9
 | | Crystal structure of human REDD1, a hypoxia-induced regulator of mTOR | | 分子名称: | DNA-damage-inducible transcript 4 protein | | 著者 | Vega-Rubin-de-Celis, S, Abdallah, Z, Brugarolas, J, Zhang, X. | | 登録日 | 2010-02-08 | | 公開日 | 2010-03-09 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural analysis and functional implications of the negative mTORC1 regulator REDD1.
Biochemistry, 49, 2010
|
|
4END
 | | Crystal structure of anti-HIV actinohivin in complex with alpha-1,2-mannobiose (P 2 21 21 form) | | 分子名称: | ACETONITRILE, Actinohivin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose | | 著者 | Hoque, M.M, Suzuki, K, Tsunoda, M, Jiang, J, Zhang, F, Takahashi, A, Naomi, O, Zhang, X, Sekiguchi, T, Tanaka, H, Omura, S, Takenaka, A. | | 登録日 | 2012-04-13 | | 公開日 | 2013-07-17 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Matured structure of anti-HIV lectin actinohivin in complex with 1,2-mannobiose
To be Published
|
|
4G3H
 | | Crystal structure of helicobacter pylori arginase | | 分子名称: | Arginase (RocF), MANGANESE (II) ION | | 著者 | Zhang, J, Zhang, X, Li, D, Hu, Y, Zou, Q, Wang, D. | | 登録日 | 2012-07-13 | | 公開日 | 2012-08-01 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure and function studies on Helicobacter pylori arginase
To be Published
|
|
1JQE
 | | Crystal Structure Analysis of Human Histamine Methyltransferase (Ile105 Polymorphic Variant) Complexed with AdoHcy and Antimalarial Drug Quinacrine | | 分子名称: | Histamine N-Methyltransferase, QUINACRINE, S-ADENOSYL-L-HOMOCYSTEINE, ... | | 著者 | Horton, J.R, Sawada, K, Nishibori, M, Zhang, X, Cheng, X. | | 登録日 | 2001-08-06 | | 公開日 | 2002-08-06 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons.
Structure, 9, 2001
|
|
2B35
 | | Crystal structure of Mycobacterium tuberculosis enoyl reductase (InhA) inhibited by triclosan | | 分子名称: | Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN | | 著者 | Sullivan, T.J, Truglio, J.J, Novichenok, P, Stratton, C, Zhang, X, Kaur, T, Johnson, F, Boyne, M.S, Amin, A. | | 登録日 | 2005-09-19 | | 公開日 | 2006-03-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | High Affinity InhA Inhibitors with Activity against Drug-Resistant Strains
of Mycobacterium tuberculosis
ACS Chem.Biol., 1, 2006
|
|
2QJO
 | | crystal structure of a bifunctional NMN adenylyltransferase/ADP ribose pyrophosphatase (NadM) complexed with ADPRP and NAD from Synechocystis sp. | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Bifunctional NMN adenylyltransferase/Nudix hydrolase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Huang, N, Sorci, L, Zhang, X, Brautigan, C, Raffaelli, N, Magni, G, Grishin, N.V, Osterman, A, Zhang, H. | | 登録日 | 2007-07-08 | | 公開日 | 2008-03-11 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Bifunctional NMN Adenylyltransferase/ADP-Ribose Pyrophosphatase: Structure and Function in Bacterial NAD Metabolism.
Structure, 16, 2008
|
|
2B36
 | | Crystal structure of Mycobacterium tuberculosis enoyl reductase (InhA) inhibited by 5-pentyl-2-phenoxyphenol | | 分子名称: | 5-PENTYL-2-PHENOXYPHENOL, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Sullivan, T.J, Truglio, J.J, Novichenok, P, Stratton, C, Zhang, X, Kaur, T, Johnson, F, Boyne, M.S, Amin, A. | | 登録日 | 2005-09-19 | | 公開日 | 2006-03-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | High Affinity InhA Inhibitors with Activity against Drug-Resistant Strains
of Mycobacterium tuberculosis
ACS Chem.Biol., 1, 2006
|
|
2QJT
 | | Crystal structure of a bifunctional NMN adenylyltransferase/ADP ribose pyrophosphatase complexed with AMP and MN ion from Francisella tularensis | | 分子名称: | ADENOSINE MONOPHOSPHATE, MANGANESE (II) ION, Nicotinamide-nucleotide adenylyltransferase | | 著者 | Huang, N, Sorci, L, Zhang, X, Brautigan, C, Raffaelli, N, Magni, G, Grishin, N.V, Osterman, A, Zhang, H. | | 登録日 | 2007-07-09 | | 公開日 | 2008-03-04 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Bifunctional NMN Adenylyltransferase/ADP-Ribose Pyrophosphatase: Structure and Function in Bacterial NAD Metabolism.
Structure, 16, 2008
|
|
3EHR
 | | Crystal Structure of Human Osteoclast Stimulating Factor | | 分子名称: | Osteoclast-stimulating factor 1 | | 著者 | Tong, S, Zhou, H, Gao, Y, Zhu, Z, Zhang, X, Teng, M, Niu, L. | | 登録日 | 2008-09-14 | | 公開日 | 2009-08-04 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of human osteoclast stimulating factor
Proteins, 75, 2009
|
|
4DHJ
 | | The structure of a ceOTUB1 ubiquitin aldehyde UBC13~Ub complex | | 分子名称: | Ubiquitin, Ubiquitin aldehyde, Ubiquitin thioesterase otubain-like, ... | | 著者 | Wiener, R, Zhang, X, Wang, T, Wolberger, C. | | 登録日 | 2012-01-27 | | 公開日 | 2012-02-22 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | The mechanism of OTUB1-mediated inhibition of ubiquitination.
Nature, 483, 2012
|
|
7LLY
 | | Oxyntomodulin-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in complex with Gs protein | | 分子名称: | Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Wootten, D, Sexton, P.M, Belousoff, M.J, Danev, R, Zhang, X, Khoshouei, M, Venugopal, H. | | 登録日 | 2021-02-04 | | 公開日 | 2022-01-12 | | 最終更新日 | 2022-01-26 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation.
Nat Commun, 13, 2022
|
|
4DKT
 | | Crystal structure of human peptidylarginine deiminase 4 in complex with N-acetyl-L-threonyl-L-alpha-aspartyl-N5-[(1E)-2-fluoroethanimidoyl]-L-ornithinamide | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Protein-arginine deiminase type-4, ... | | 著者 | Jones, J.E, Slack, J.L, Fang, P, Zhang, X, Subramanian, V, Causey, C.P, Coonrod, S.A, Guo, M, Thompson, P.R. | | 登録日 | 2012-02-04 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | | 主引用文献 | Synthesis and Screening of a Haloacetamidine Containing Library To Identify PAD4 Selective Inhibitors.
Acs Chem.Biol., 7, 2012
|
|
7LLL
 | | Exendin-4-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in complex with Gs protein | | 分子名称: | Exendin-4, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Wootten, D, Sexton, P.M, Belousoff, M.J, Danev, R, Zhang, X, Khoshouei, M, Venugopal, H. | | 登録日 | 2021-02-04 | | 公開日 | 2022-01-12 | | 最終更新日 | 2022-01-26 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation.
Nat Commun, 13, 2022
|
|
4DHZ
 | | The structure of h/ceOTUB1-ubiquitin aldehyde-UBC13~Ub | | 分子名称: | Ubiquitin, Ubiquitin aldehyde, Ubiquitin thioesterase otubain-like, ... | | 著者 | Wiener, R, Zhang, X, Wang, T, Wolberger, C. | | 登録日 | 2012-01-30 | | 公開日 | 2012-02-22 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | The mechanism of OTUB1-mediated inhibition of ubiquitination.
Nature, 483, 2012
|
|
4C6S
 | | Crystal structure of the TIR domain from the Arabidopsis Thaliana disease resistance protein RRS1 | | 分子名称: | GLYCEROL, PROBABLE WRKY TRANSCRIPTION FACTOR 52, SODIUM ION, ... | | 著者 | Wan, L, Williams, S.J, Sohn, K.H, Bernoux, M, Ma, Y, Segonzac, C, Ve, T, Sarris, P, Ericsson, D.J, Saucet, S.B, Zhang, X, Parker, J, Dodds, P.N, Jones, J.D.G, Kobe, B. | | 登録日 | 2013-09-19 | | 公開日 | 2014-05-28 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.751 Å) | | 主引用文献 | Structural Basis for Assembly and Function of a Heterodimeric Plant Immune Receptor.
Science, 344, 2014
|
|
4C6R
 | | Crystal structure of the TIR domain from the Arabidopsis Thaliana disease resistance protein RPS4 | | 分子名称: | DISEASE RESISTANCE PROTEIN RPS4 | | 著者 | Williams, S.J, Sohn, K.H, Wan, L, Bernoux, M, Ma, Y, Segonzac, C, Ve, T, Sarris, P, Ericsson, D.J, Saucet, S.B, Zhang, X, Parker, J, Dodds, P.N, Jones, J.D.G, Kobe, B. | | 登録日 | 2013-09-19 | | 公開日 | 2014-05-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural Basis for Assembly and Function of a Heterodimeric Plant Immune Receptor.
Science, 344, 2014
|
|
4DFF
 | | The SAR development of dihydroimidazoisoquinoline derivatives as phosphodiesterase 10A inhibitors for the treatment of schizophrenia | | 分子名称: | 8,9-dimethoxy-1-(1,3-thiazol-5-yl)-5,6-dihydroimidazo[5,1-a]isoquinoline, MAGNESIUM ION, ZINC ION, ... | | 著者 | Ho, G.D, Seganish, W.M, Bercovici, A, Tulshian, D, Greenlee, W.J, Van Rijn, R, Hruza, A, Xiao, L, Rindgen, D, Mullins, D, Guzzi, M, Zhang, X, Bleichardt, C, Hodgson, R. | | 登録日 | 2012-01-23 | | 公開日 | 2012-03-14 | | 最終更新日 | 2012-04-04 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | The SAR development of dihydroimidazoisoquinoline derivatives as phosphodiesterase 10A inhibitors for the treatment of schizophrenia.
Bioorg.Med.Chem.Lett., 22, 2012
|
|
4DHI
 | | Structure of C. elegans OTUB1 bound to human UBC13 | | 分子名称: | Ubiquitin thioesterase otubain-like, Ubiquitin-conjugating enzyme E2 N | | 著者 | Wiener, R, Zhang, X, Wang, T, Wolberger, C. | | 登録日 | 2012-01-27 | | 公開日 | 2012-02-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The mechanism of OTUB1-mediated inhibition of ubiquitination.
Nature, 483, 2012
|
|
3EHQ
 | | Crystal Structure of Human Osteoclast Stimulating Factor | | 分子名称: | 1,2-ETHANEDIOL, Osteoclast-stimulating factor 1 | | 著者 | Tong, S, Zhou, H, Gao, Y, Zhu, Z, Zhang, X, Teng, M, Niu, L. | | 登録日 | 2008-09-14 | | 公開日 | 2009-08-04 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Crystal structure of human osteoclast stimulating factor
Proteins, 75, 2009
|
|
3GT8
 | | Crystal structure of the inactive EGFR kinase domain in complex with AMP-PNP | | 分子名称: | Epidermal growth factor receptor, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Jura, N, Endres, N.F, Engel, K, Deindl, S, Das, R, Lamers, M.H, Wemmer, D.E, Zhang, X, Kuriyan, J. | | 登録日 | 2009-03-27 | | 公開日 | 2009-07-21 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.955 Å) | | 主引用文献 | Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment.
Cell(Cambridge,Mass.), 137, 2009
|
|
