8Y8H

Structure of HCoV-HKU1C spike in the glycan-activated-2up conformation

Summary for 8Y8H

• Entry DOI: 10.2210/pdb8y8h/pdb
• EMDB information: 39046
• Descriptor: Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
• Functional Keywords: hku1c, spike, tmprss2, viral protein
• Biological source: Human coronavirus HKU1 (isolate N5) (HCoV-HKU1)
• Total number of polymer chains: 3
• Total formula weight: 423160.65

Authors

Lu, Y.C.,Zhang, X.,Wang, H.F.,Sun, L.,Yang, H.T. (deposition date: 2024-02-06, release date: 2024-07-17)

• Primary citation: Wang, H.,Liu, X.,Zhang, X.,Zhao, Z.,Lu, Y.,Pu, D.,Zhang, Z.,Chen, J.,Wang, Y.,Li, M.,Dong, X.,Duan, Y.,He, Y.,Mao, Q.,Guo, H.,Sun, H.,Zhou, Y.,Yang, Q.,Gao, Y.,Yang, X.,Cao, H.,Guddat, L.,Sun, L.,Rao, Z.,Yang, H.; TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.; Cell, 2024; PubMed: 38964329; DOI: 10.1016/j.cell.2024.06.016

Experimental method