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5ABF

Structure of GH84 with ligand

Summary for 5ABF
Entry DOI10.2210/pdb5abf/pdb
Related5ABE 5ABG 5ABH
DescriptorO-GLCNACASE BT_4395, 1,2-ETHANEDIOL, 2-[(2S,3R,4R,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)-1-pentyl-pyrrolidin-2-yl]-N-methyl-ethanamide, ... (6 entities in total)
Functional Keywordshydrolase, tim-barrel, inhibitor
Biological sourceBACTEROIDES THETAIOTAOMICRON
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Total number of polymer chains2
Total formula weight167741.75
Authors
Bergeron-Brlek, M.,Goodwin-Tindall, J.,Cekic, N.,Varghese, V.,Zandberg, W.F.,Shan, X.,Roth, C.,Chan, S.,Davies, G.J.,Vocadlo, D.J.,Britton, R. (deposition date: 2015-08-05, release date: 2015-11-18, Last modification date: 2019-10-23)
Primary citationBergeron-Brlek, M.,Goodwin-Tindall, J.,Cekic, N.,Roth, C.,Zandberg, W.F.,Shan, X.,Varghese, V.,Chan, S.,Davies, G.J.,Vocadlo, D.J.,Britton, R.
A Convenient Approach to Stereoisomeric Iminocyclitols: Generation of Potent Brain-Permeable Oga Inhibitors.
Angew.Chem.Int.Ed.Engl., 54:15429-, 2015
Cited by
PubMed: 26545827
DOI: 10.1002/ANIE.201507985
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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