5ABH
Structure of GH84 with ligand
Summary for 5ABH
Entry DOI | 10.2210/pdb5abh/pdb |
Related | 5ABE 5ABF 5ABG |
Descriptor | O-GLCNACASE BT_4395, CHLORIDE ION, 2-[(2R,3S,4R,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)-1-pentyl-pyrrolidin-2-yl]-N-methyl-ethanamide, ... (6 entities in total) |
Functional Keywords | hydrolase, tim-barrel, inhibitor |
Biological source | BACTEROIDES THETAIOTAOMICRON |
Total number of polymer chains | 2 |
Total formula weight | 167763.18 |
Authors | Bergeron-Brlek, M.,Goodwin-Tindall, J.,Cekic, N.,Varghese, V.,Zandberg, W.F.,Shan, X.,Roth, C.,Chan, S.,Davies, G.J.,Vocadlo, D.J.,Britton, R. (deposition date: 2015-08-05, release date: 2015-11-18, Last modification date: 2024-05-08) |
Primary citation | Bergeron-Brlek, M.,Goodwin-Tindall, J.,Cekic, N.,Roth, C.,Zandberg, W.F.,Shan, X.,Varghese, V.,Chan, S.,Davies, G.J.,Vocadlo, D.J.,Britton, R. A Convenient Approach to Stereoisomeric Iminocyclitols: Generation of Potent Brain-Permeable Oga Inhibitors. Angew.Chem.Int.Ed.Engl., 54:15429-, 2015 Cited by PubMed: 26545827DOI: 10.1002/ANIE.201507985 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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