8E7O
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8DNQ
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8F4B
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8F1F
| Structure of K48-linked tri-ubiquitin in complex with cyclic peptide | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Non-proteinogenic cyclic peptide (inhibitor), ... | 著者 | Lubkowski, J, Fushman, D, Lemma, B. | 登録日 | 2022-11-05 | 公開日 | 2023-11-01 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Mechanism of selective recognition of Lys48-linked polyubiquitin by macrocyclic peptide inhibitors of proteasomal degradation. Nat Commun, 14, 2023
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3WMF
| Crystal structure of an inward-facing eukaryotic ABC multitrug transporter G277V/A278V/A279V mutant | 分子名称: | ATP-binding cassette, sub-family B, member 1, ... | 著者 | Kodan, A, Yamaguchi, T, Nakatsu, T, Kato, H. | 登録日 | 2013-11-18 | 公開日 | 2014-03-19 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog. Proc.Natl.Acad.Sci.USA, 111, 2014
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3WME
| Crystal structure of an inward-facing eukaryotic ABC multidrug transporter | 分子名称: | ATP-binding cassette, sub-family B, member 1, ... | 著者 | Kodan, A, Yamaguchi, T, Nakatsu, T, Kato, H. | 登録日 | 2013-11-18 | 公開日 | 2014-03-19 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.751 Å) | 主引用文献 | Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog. Proc.Natl.Acad.Sci.USA, 111, 2014
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5GVS
| Crystal structure of the DDX41 DEAD domain in an apo open form | 分子名称: | Probable ATP-dependent RNA helicase DDX41 | 著者 | Omura, H, Oikawa, D, Nakane, T, Kato, M, Ishii, R, Goto, Y, Suga, H, Ishitani, R, Tokunaga, F, Nureki, O. | 登録日 | 2016-09-06 | 公開日 | 2016-10-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide Sci Rep, 6, 2016
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5GVR
| Crystal structure of the DDX41 DEAD domain in an apo closed form | 分子名称: | (2S)-2-hydroxybutanedioic acid, Probable ATP-dependent RNA helicase DDX41 | 著者 | Omura, H, Oikawa, D, Nakane, T, Kato, M, Ishii, R, Goto, Y, Suga, H, Ishitani, R, Tokunaga, F, Nureki, O. | 登録日 | 2016-09-06 | 公開日 | 2016-10-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide Sci Rep, 6, 2016
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6U4A
| BRD3-BD1 in complex with the cyclic peptide 3.1_3 | 分子名称: | Bromodomain-containing protein 3, GLYCEROL, SULFATE ION, ... | 著者 | Patel, K, Walshe, J.L, Walport, L.J, Mackay, J.P. | 登録日 | 2019-08-24 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Cyclic peptides can engage a single binding pocket through highly divergent modes. Proc.Natl.Acad.Sci.USA, 117, 2020
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6U6K
| BRD4-BD1 in complex with the cyclic peptide 3.1_3 | 分子名称: | Bromodomain-containing protein 4, cyclic peptide 3.1_3 | 著者 | Patel, K, Walshe, J.L, Walport, L.J, Mackay, J.P. | 登録日 | 2019-08-30 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Cyclic peptides can engage a single binding pocket through highly divergent modes. Proc.Natl.Acad.Sci.USA, 117, 2020
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6U71
| BRD2-BD2 in complex with the cyclic peptide 3.1_3 | 分子名称: | Bromodomain-containing protein 2, cyclic peptide 3.1_3 | 著者 | Patel, K, Walshe, J.L, Walport, L.J, Mackay, J.P. | 登録日 | 2019-08-31 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Cyclic peptides can engage a single binding pocket through highly divergent modes. Proc.Natl.Acad.Sci.USA, 117, 2020
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6U8G
| BRD4-BD2 in complex with the cyclic peptide 3.1_2_AcK7toA | 分子名称: | Bromodomain-containing protein 4, cyclic peptide 3.1_2_AcK7toA | 著者 | Patel, K, Walshe, J.L, Walport, L.J, Mackay, J.P, Mouradian, K.S. | 登録日 | 2019-09-05 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Cyclic peptides can engage a single binding pocket through highly divergent modes. Proc.Natl.Acad.Sci.USA, 117, 2020
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6U72
| BRD4-BD1 in complex with the cyclic peptide 3.1_2_AcK5toA | 分子名称: | 3.1_2_AcK5toA, AMINO GROUP, Bromodomain-containing protein 4 | 著者 | Patel, K, Walshe, J.L, Walport, L.J, Mackay, J.P, Mouradian, K.S. | 登録日 | 2019-08-31 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Cyclic peptides can engage a single binding pocket through highly divergent modes. Proc.Natl.Acad.Sci.USA, 117, 2020
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6U61
| BRD2-BD1 in complex with the cyclic peptide 3.1_3 | 分子名称: | Bromodomain-containing protein 2, ZINC ION, cyclic peptide 3.1_3 | 著者 | Patel, K, Walshe, J.L, Walport, L.J, Mackay, J.P. | 登録日 | 2019-08-28 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Cyclic peptides can engage a single binding pocket through highly divergent modes. Proc.Natl.Acad.Sci.USA, 117, 2020
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6U6L
| BRD4-BD2 in complex with the cyclic peptide 3.1_2 | 分子名称: | AMINO GROUP, Bromodomain-containing protein 4, Cyclic peptide 3.1_2, ... | 著者 | Patel, K, Walshe, J.L, Walport, L.J, Mackay, J.P. | 登録日 | 2019-08-30 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Cyclic peptides can engage a single binding pocket through highly divergent modes. Proc.Natl.Acad.Sci.USA, 117, 2020
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6U8H
| BRD2-BD1 in complex with the cyclic peptide 3.2_2 | 分子名称: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, AMINO GROUP, Bromodomain-containing protein 2, ... | 著者 | Patel, K, Walshe, J.L, Walport, L.J, Mackay, J.P. | 登録日 | 2019-09-05 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Cyclic peptides can engage a single binding pocket through highly divergent modes. Proc.Natl.Acad.Sci.USA, 117, 2020
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6U8M
| BRD4-BD1 in complex with the cyclic peptide 3.2_1 | 分子名称: | AMINO GROUP, Bromodomain-containing protein 4, cyclic peptide 3.2_1 | 著者 | Patel, K, Walshe, J.L, Walport, L.J, Mackay, J.P. | 登録日 | 2019-09-05 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Cyclic peptides can engage a single binding pocket through highly divergent modes. Proc.Natl.Acad.Sci.USA, 117, 2020
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7E5E
| Crystal structure of GDP-bound GNAS in complex with the cyclic peptide inhibitor GD20 | 分子名称: | CHLORIDE ION, GD20, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Hu, Q, Dai, S, Shokat, K.M. | 登録日 | 2021-02-18 | 公開日 | 2022-03-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | State-selective modulation of heterotrimeric G alpha s signaling with macrocyclic peptides. Cell, 185, 2022
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7VG7
| Plexin B1 extracellular fragment in complex with lasso-grafted PB1m6A9 peptide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-B1, TRIETHYLENE GLYCOL, ... | 著者 | Sugano, N.N, Hirata, K, Yamashita, K, Yamamoto, M, Arimori, T, Takagi, J. | 登録日 | 2021-09-14 | 公開日 | 2022-08-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | De novo Fc-based receptor dimerizers differentially modulate PlexinB1 function. Structure, 30, 2022
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7VF3
| Plexin B1 extracellular fragment in complex with lasso-grafted PB1m7 peptide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Plexin-B1, ... | 著者 | Sugano, N.N, Hirata, K, Yamashita, K, Yamamoto, M, Arimori, T, Takagi, J. | 登録日 | 2021-09-10 | 公開日 | 2022-08-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | De novo Fc-based receptor dimerizers differentially modulate PlexinB1 function. Structure, 30, 2022
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3VVP
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3VVR
| Crystal structure of MATE in complex with MaD5 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Putative uncharacterized protein, macrocyclic peptide | 著者 | Tanaka, Y, Ishitani, R, Nureki, O. | 登録日 | 2012-07-27 | 公開日 | 2013-04-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis for the drug extrusion mechanism by a MATE multidrug transporter. Nature, 496, 2013
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3VVS
| Crystal structure of MATE in complex with MaD3S | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Putative uncharacterized protein, macrocyclic peptide | 著者 | Tanaka, Y, Ishitani, R, Nureki, O. | 登録日 | 2012-07-27 | 公開日 | 2013-04-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for the drug extrusion mechanism by a MATE multidrug transporter. Nature, 496, 2013
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3VVO
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3VVN
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