8CV5

Peptide 4.2B in complex with BRD3.2

Summary for 8CV5

• Entry DOI: 10.2210/pdb8cv5/pdb
• Descriptor: Bromodomain-containing protein 3, Peptide 4.2E, ACETYL GROUP, ... (5 entities in total)
• Functional Keywords: cyclic peptide inhibitor bromodomain, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 16078.55

Authors

Franck, C.,Mackay, J.P. (deposition date: 2022-05-18, release date: 2023-05-24, Last modification date: 2023-12-06)

• Primary citation: Franck, C.,Patel, K.,Walport, L.J.,Christie, M.,Norman, A.,Passioura, T.,Suga, H.,Payne, R.J.,Mackay, J.P.; Discovery and characterization of cyclic peptides selective for the C-terminal bromodomains of BET family proteins.; Structure, 31:912-923.e4, 2023; PubMed: 37269828; DOI: 10.1016/j.str.2023.05.009

Experimental method

X-RAY DIFFRACTION (1.47 Å)