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8E7O

CRYSTAL STRUCTURE OF LYS48-LINKED TETRAUBIQUITIN

Summary for 8E7O
Entry DOI10.2210/pdb8e7o/pdb
DescriptorUbiquitin, SULFATE ION, ... (4 entities in total)
Functional Keywordsdegradation, polypeptide, homeostasis, post-translational modification, polyubiquitin chain, signaling protein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains4
Total formula weight34719.59
Authors
Lemma, B.E.,Fushman, D. (deposition date: 2022-08-24, release date: 2022-11-02, Last modification date: 2023-11-15)
Primary citationLemma, B.,Zhang, D.,Vamisetti, G.B.,Wentz, B.G.,Suga, H.,Brik, A.,Lubkowski, J.,Fushman, D.
Mechanism of selective recognition of Lys48-linked polyubiquitin by macrocyclic peptide inhibitors of proteasomal degradation.
Nat Commun, 14:7212-7212, 2023
Cited by
PubMed: 37938554
DOI: 10.1038/s41467-023-43025-4
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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