7UHB
 
 | |
6DG5
 | | Structure of a de novo designed Interleukin-2/Interleukin-15 mimetic complex with IL-2Rb and IL-2Rg | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, ... | | 著者 | Jude, K.M, Silva, D.-A, Yu, S, Baker, D, Garcia, K.C. | | 登録日 | 2018-05-16 | | 公開日 | 2019-01-16 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.516 Å) | | 主引用文献 | De novo design of potent and selective mimics of IL-2 and IL-15.
Nature, 565, 2019
|
|
6DG6
 | | Structure of a de novo designed Interleukin-2/Interleukin-15 mimetic | | 分子名称: | Neoleukin-2/15 | | 著者 | Jude, K.M, Silva, D.-A, Yu, S, Baker, D, Garcia, K.C. | | 登録日 | 2018-05-16 | | 公開日 | 2019-01-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | | 主引用文献 | De novo design of potent and selective mimics of IL-2 and IL-15.
Nature, 565, 2019
|
|
8T5E
 | | De novo design of high-affinity protein binders to bioactive helical peptides | | 分子名称: | Bcl-2-like protein 11, Bim_fulldiff | | 著者 | Torres, S.V, Leung, P.J.Y, Bera, A.K, Baker, D, Kang, A. | | 登録日 | 2023-06-13 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | De novo design of high-affinity binders of bioactive helical peptides.
Nature, 626, 2024
|
|
8T5F
 | | De novo design of high-affinity protein binders to bioactive helical peptides | | 分子名称: | Parathyroid hormone | | 著者 | Torres, S.V, Leung, P.J.Y, Bera, A.K, Baker, D, Kang, A. | | 登録日 | 2023-06-13 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | De novo design of high-affinity binders of bioactive helical peptides.
Nature, 626, 2024
|
|
6TMS
 | | Crystal structure of a de novo designed hexameric helical-bundle protein | | 分子名称: | SULFATE ION, a novel designed pore protein, affinity purification tag | | 著者 | Xu, C, Pei, X.Y, Luisi, B.F, Baker, D. | | 登録日 | 2019-12-05 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Computational design of transmembrane pores.
Nature, 585, 2020
|
|
6TJ1
 | | Crystal structure of a de novo designed hexameric helical-bundle protein | | 分子名称: | De novo designed WSHC6, purification tag | | 著者 | Xu, C, Pei, X.Y, Luisi, B.F, Baker, D. | | 登録日 | 2019-11-23 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Computational design of transmembrane pores.
Nature, 585, 2020
|
|
6U1S
 | | Cryo-EM structure of a de novo designed 16-helix transmembrane nanopore, TMHC8_R. | | 分子名称: | de novo designed 16-helix transmembrane nanopore, TMHC8_R | | 著者 | Johnson, M.J, Reggiano, G, Xu, C, Lu, P, Hsia, Y, Brunette, T.J, DiMaio, F, Baker, D, Kollman, J. | | 登録日 | 2019-08-16 | | 公開日 | 2020-08-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | | 主引用文献 | Computational Design of Transmembrane Channels
To Be Published
|
|
4EFI
 | | Crystal Structure of 3-oxoacyl-(Acyl-carrier protein) Synthase from Burkholderia Xenovorans LB400 | | 分子名称: | 3-oxoacyl-(Acyl-carrier protein) synthase, CHLORIDE ION, FORMIC ACID, ... | | 著者 | Seattle Structural Genomics Center for Infectious Disease, Craig, T.K, Abendroth, J, Staker, B, Stewart, L, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | 登録日 | 2012-03-29 | | 公開日 | 2012-04-11 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Combining functional and structural genomics to sample the essential Burkholderia structome.
Plos One, 8, 2013
|
|
4F2G
 | | The Crystal Structure of Ornithine carbamoyltransferase from Burkholderia thailandensis E264 | | 分子名称: | 1,2-ETHANEDIOL, Ornithine carbamoyltransferase 1, PHOSPHATE ION | | 著者 | Craig, T.K, Fox, D, Staker, B, Stewart, L, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | 登録日 | 2012-05-07 | | 公開日 | 2012-05-30 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Combining functional and structural genomics to sample the essential Burkholderia structome.
Plos One, 8, 2013
|
|
5VMR
 | |
5KOB
 | |
6M6Z
 | | A de novo designed transmembrane nanopore, TMH4C4 | | 分子名称: | TMH4C4 | | 著者 | Lu, P, Xu, C, Reggiano, G, Xu, Q, DiMaio, F, Baker, D. | | 登録日 | 2020-03-16 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | | 主引用文献 | Computational design of transmembrane pores.
Nature, 585, 2020
|
|
6O35
 | |
7UBC
 | |
7UBF
 | |
7UBD
 | |
7UCP
 | | computationally designed macrocycle | | 分子名称: | computationally designed cyclic peptide D8.3.p2 | | 著者 | Bhardwaj, G, Baker, D, Rettie, S, Glynn, C, Sawaya, M. | | 登録日 | 2022-03-17 | | 公開日 | 2022-09-14 | | 最終更新日 | 2022-09-28 | | 実験手法 | X-RAY DIFFRACTION (0.85 Å) | | 主引用文献 | Accurate de novo design of membrane-traversing macrocycles.
Cell, 185, 2022
|
|
7UBE
 | |
7UBI
 | |
7UBH
 | |
7UBG
 | |
7UZL
 | |
7KNA
 | | Localized reconstruction of the H1 A/Michigan/45/2015 ectodomain displayed at the surface of I53_dn5 nanoparticle | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin,I53_dn5 | | 著者 | Acton, O.J, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | 登録日 | 2020-11-04 | | 公開日 | 2021-03-31 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Quadrivalent influenza nanoparticle vaccines induce broad protection.
Nature, 592, 2021
|
|
8GJI
 | | De novo design of high-affinity protein binders to bioactive helical peptides | | 分子名称: | GCG binder, Glucagon | | 著者 | Torres, S.V, Leung, P.J.Y, Bera, A.K, Baker, D, Kang, A. | | 登録日 | 2023-03-15 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | De novo design of high-affinity binders of bioactive helical peptides.
Nature, 626, 2024
|
|
