6WRV

Crystal structure of computationally designed protein 3DS18 in complex with the human Transferrin receptor ectodomain

Summary for 6WRV

Entry DOI	10.2210/pdb6wrv/pdb
Descriptor	Transferrin receptor protein 1, Computationally designed protein 3DS18, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	complex, beta sheet, receptor, de novo protein, de novo protein-metal transport complex, de novo protein/metal transport
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	253314.24
Authors	Abraham, J.,Baker, D.,Sahtoe, D.D.,Coscia, A.,Clark, L.,Olal, D. (deposition date: 2020-04-30, release date: 2021-04-28, Last modification date: 2023-10-18)
Primary citation	Sahtoe, D.D.,Coscia, A.,Mustafaoglu, N.,Miller, L.M.,Olal, D.,Vulovic, I.,Yu, T.Y.,Goreshnik, I.,Lin, Y.R.,Clark, L.,Busch, F.,Stewart, L.,Wysocki, V.H.,Ingber, D.E.,Abraham, J.,Baker, D. Transferrin receptor targeting by de novo sheet extension. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 33879614 DOI: 10.1073/pnas.2021569118 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.47 Å)

Structure validation