6WRX
Crystal structure of computationally designed protein 2DS25.1 in complex with the human Transferrin receptor ectodomain
Summary for 6WRX
Entry DOI | 10.2210/pdb6wrx/pdb |
Descriptor | Transferrin receptor protein 1, Computationally designed protein 2DS25.1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | complex, beta sheet, receptor, de novo protein, de novo protein-metal transport complex, de novo protein/metal transport |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 167017.81 |
Authors | Abraham, J.,Coscia, A.,Olal, D.,Sahtoe, D.D.,Baker, D.,Clark, L. (deposition date: 2020-04-30, release date: 2021-04-28, Last modification date: 2023-10-18) |
Primary citation | Sahtoe, D.D.,Coscia, A.,Mustafaoglu, N.,Miller, L.M.,Olal, D.,Vulovic, I.,Yu, T.Y.,Goreshnik, I.,Lin, Y.R.,Clark, L.,Busch, F.,Stewart, L.,Wysocki, V.H.,Ingber, D.E.,Abraham, J.,Baker, D. Transferrin receptor targeting by de novo sheet extension. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 33879614DOI: 10.1073/pnas.2021569118 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.07 Å) |
Structure validation
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