7N1K

Crystal structure of a de novo-designed mini-protein targeting FGFR

Summary for 7N1K

Entry DOI	10.2210/pdb7n1k/pdb
Related	7N1J
Descriptor	Binder (1 entity in total)
Functional Keywords	binder, de novo protein
Biological source	synthetic construct
Total number of polymer chains	1
Total formula weight	7535.81
Authors	Park, J.S.,Lee, S. (deposition date: 2021-05-27, release date: 2022-04-06, Last modification date: 2024-04-03)
Primary citation	Cao, L.,Coventry, B.,Goreshnik, I.,Huang, B.,Sheffler, W.,Park, J.S.,Jude, K.M.,Markovic, I.,Kadam, R.U.,Verschueren, K.H.G.,Verstraete, K.,Walsh, S.T.R.,Bennett, N.,Phal, A.,Yang, A.,Kozodoy, L.,DeWitt, M.,Picton, L.,Miller, L.,Strauch, E.M.,DeBouver, N.D.,Pires, A.,Bera, A.K.,Halabiya, S.,Hammerson, B.,Yang, W.,Bernard, S.,Stewart, L.,Wilson, I.A.,Ruohola-Baker, H.,Schlessinger, J.,Lee, S.,Savvides, S.N.,Garcia, K.C.,Baker, D. Design of protein-binding proteins from the target structure alone. Nature, 605:551-560, 2022 Cited by PubMed: 35332283 DOI: 10.1038/s41586-022-04654-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.01 Å)

Structure validation