6MS9
 
 | | GDP-bound KRAS P34R mutant | | 分子名称: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Bera, A.K, Westover, K.D. | | 登録日 | 2018-10-16 | | 公開日 | 2020-04-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | GTP hydrolysis is modulated by Arg34 in the RASopathy-associated KRASP34R.
Birth Defects Res, 112, 2020
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2WY4
 | | Structure of bacterial globin from Campylobacter jejuni at 1.35 A resolution | | 分子名称: | CYANIDE ION, PROTOPORPHYRIN IX CONTAINING FE, SINGLE DOMAIN HAEMOGLOBIN | | 著者 | Barynin, V.V, Sedelnikova, S.E, Shepherd, M, Wu, G, Poole, R.K, Rice, D.W. | | 登録日 | 2009-11-11 | | 公開日 | 2010-02-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | The Single-Domain Globin from the Pathogenic Bacterium Campylobacter Jejuni: Novel D-Helix Conformation, Proximal Hydrogen Bonding that Influences Ligand Binding, and Peroxidase-Like Redox Properties.
J.Biol.Chem., 285, 2010
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5H19
 | | EED in complex with PRC2 allosteric inhibitor EED162 | | 分子名称: | 5-(furan-2-ylmethylamino)-9-(phenylmethyl)-8,10-dihydro-7H-[1,2,4]triazolo[3,4-a][2,7]naphthyridine-6-carbonitrile, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED | | 著者 | Zhao, K, Zhao, M, Luo, X, Zhang, H. | | 登録日 | 2016-10-08 | | 公開日 | 2017-01-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED
PLoS ONE, 12, 2017
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6O36
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2KM8
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6LP5
 | | Structure of Sinonovacula constricta ferritin | | 分子名称: | FE (II) ION, FE (III) ION, Ferritin, ... | | 著者 | Su, X.R, Ming, T.H, Su, C. | | 登録日 | 2020-01-08 | | 公開日 | 2020-04-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Crystallographic characterization of ferritin from Sinonovacula constricta.
Biochem.Biophys.Res.Commun., 524, 2020
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7LR3
 | | Complex of Fab 2/6.14 with domain 3 of P. berghei HAP2 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, D3_2/6.14 Fab heavy chain, D3_2/6.14 Fab light chain, ... | | 著者 | Feng, J, Dong, X.C, Lu, C.F, Springer, T.A. | | 登録日 | 2021-02-15 | | 公開日 | 2021-12-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2.
Elife, 10, 2021
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7LR4
 | | Complex of Fab 2/1.12 with domain 3 of P. berghei HAP2 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, D3_2/1.12 Fab heavy chain, D3_2/1.12 Fab light chain, ... | | 著者 | Feng, J, Dong, X.C, Su, Y, Lu, X.F, Springer, T.A. | | 登録日 | 2021-02-15 | | 公開日 | 2021-12-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2.
Elife, 10, 2021
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4YR8
 | | Crystal structure of JNK in complex with a regulator protein | | 分子名称: | CHLORIDE ION, Dual specificity protein phosphatase 16, Mitogen-activated protein kinase 8 | | 著者 | Liu, X, Wang, J, Wu, J.W, Wang, Z.X. | | 登録日 | 2015-03-14 | | 公開日 | 2016-03-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation.
Nat Commun, 7, 2016
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5YAN
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5ZM7
 | | Crystal structure of ORP1-ORD in complex with cholesterol at 3.4 A resolution | | 分子名称: | CHOLESTEROL, Oxysterol-binding protein-related protein 1 | | 著者 | Dong, J, Wang, J, Wu, J.W. | | 登録日 | 2018-04-01 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.401 Å) | | 主引用文献 | Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2.
Nat Commun, 10, 2019
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5ZM6
 | | Crystal structure of ORP1-ORD in complex with PI(4,5)P2 | | 分子名称: | ACETATE ION, Oxysterol-binding protein-related protein 1, [(2~{S})-1-octadecanoyloxy-3-[oxidanyl-[(1~{R},2~{R},3~{S},4~{S},5~{S},6~{S})-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propan-2-yl] icosa-5,8,11,14-tetraenoate | | 著者 | Dong, J, Wang, J, Luo, Z, Wu, J.W. | | 登録日 | 2018-04-01 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2.
Nat Commun, 10, 2019
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7MDP
 | | KRas G12C in complex with G-2897 | | 分子名称: | 1,2-ETHANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, 4-(trifluoromethyl)-1,3-benzothiazol-2-amine, ... | | 著者 | Oh, A, Frank, Y, Wang, W. | | 登録日 | 2021-04-05 | | 公開日 | 2022-03-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors.
Nat.Biotechnol., 40, 2022
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8GY1
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8HCT
 | | Crystal structure of Cu2+ binding to Dendrorhynchus zhejiangensis ferritin | | 分子名称: | COPPER (II) ION, FE (III) ION, Ferritin, ... | | 著者 | Ming, T.H, Su, X.R, Huo, C.H. | | 登録日 | 2022-11-03 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Structural and Biochemical Characterization of Silver/Copper Binding by Dendrorhynchus zhejiangensis Ferritin.
Polymers (Basel), 15, 2023
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6JPM
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3GA3
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3GXB
 | | Crystal structure of VWF A2 domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... | | 著者 | Zhou, Y.F, Springer, T.A. | | 登録日 | 2009-04-02 | | 公開日 | 2009-05-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural specializations of A2, a force-sensing domain in the ultralarge vascular protein von Willebrand factor.
Proc.Natl.Acad.Sci.USA, 106, 2009
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7VHR
 | | Apostichopus japonicus ferritin | | 分子名称: | Ferritin, MAGNESIUM ION | | 著者 | Wu, Y, Su, X.R, Ming, T.H. | | 登録日 | 2021-09-22 | | 公開日 | 2022-03-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.756 Å) | | 主引用文献 | Crystallographic characterization of a marine invertebrate ferritin from the sea cucumber Apostichopus japonicus.
Febs Open Bio, 12, 2022
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5JLE
 | | Crystal structure of SETD2 bound to SAH | | 分子名称: | Histone-lysine N-methyltransferase SETD2, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | | 著者 | Li, H, Yang, S, Zheng, X. | | 登録日 | 2016-04-27 | | 公開日 | 2016-11-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Molecular basis for oncohistone H3 recognition by SETD2 methyltransferase
Genes Dev., 30, 2016
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5JLB
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5JJY
 | | Crystal structure of SETD2 bound to histone H3.3 K36M peptide | | 分子名称: | Histone H3.3, Histone-lysine N-methyltransferase SETD2, S-ADENOSYL-L-HOMOCYSTEINE, ... | | 著者 | Yang, S, Zheng, X, Li, H. | | 登録日 | 2016-04-25 | | 公開日 | 2016-11-02 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.053 Å) | | 主引用文献 | Molecular basis for oncohistone H3 recognition by SETD2 methyltransferase
Genes Dev., 30, 2016
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8T9H
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7RP3
 | | Crystal structure of GNE-1952 alkylated KRAS G12C in complex with 2H11 CLAMP | | 分子名称: | 1,2-ETHANEDIOL, 1-[4-[6-chloranyl-7-(5-methyl-1~{H}-indazol-4-yl)quinazolin-4-yl]piperazin-1-yl]propan-1-one, GLYCEROL, ... | | 著者 | Oh, A, Tam, C, Wang, W. | | 登録日 | 2021-08-03 | | 公開日 | 2022-03-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors.
Nat.Biotechnol., 40, 2022
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7RP4
 | | Crystal structure of KRAS G12C in complex with GNE-1952 | | 分子名称: | 1-[4-[6-chloranyl-7-(5-methyl-1~{H}-indazol-4-yl)quinazolin-4-yl]piperazin-1-yl]propan-1-one, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Oh, A, Tam, C, Wang, W. | | 登録日 | 2021-08-03 | | 公開日 | 2022-03-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors.
Nat.Biotechnol., 40, 2022
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