8BNZ
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![BU of 8bnz by Molmil](/molmil-images/mine/8bnz) | BAM-EspP complex structure with BamA-G431C/EspP-N1293C mutations in nanodisc | 分子名称: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | 著者 | Shen, C, Chang, S, Luo, Q, Zhang, Z, Xie, T, Luo, B, Lu, G, Zhu, X, Wei, X, Dong, C, Zhou, R, Zhang, X, Tang, X, Dong, H. | 登録日 | 2022-11-14 | 公開日 | 2023-04-26 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural basis of BAM-mediated outer membrane beta-barrel protein assembly. Nature, 617, 2023
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7D90
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![BU of 7d90 by Molmil](/molmil-images/mine/7d90) | human potassium-chloride co-transporter KCC3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, potassium-chloride cotransporter 3 | 著者 | Xie, Y, Chang, S, Zhao, C, Ye, S, Guo, J. | 登録日 | 2020-10-12 | 公開日 | 2020-12-30 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structures and an activation mechanism of human potassium-chloride cotransporters. Sci Adv, 6, 2020
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7D8Z
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![BU of 7d8z by Molmil](/molmil-images/mine/7d8z) | human potassium-chloride co-transporter KCC2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, potassium-chloride cotransporter 2 | 著者 | Xie, Y, Chang, S, Zhao, C, Ye, S, Guo, J. | 登録日 | 2020-10-11 | 公開日 | 2020-12-30 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structures and an activation mechanism of human potassium-chloride cotransporters. Sci Adv, 6, 2020
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5CYU
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![BU of 5cyu by Molmil](/molmil-images/mine/5cyu) | Structure of the soluble domain of EccB1 from the Mycobacterium smegmatis ESX-1 secretion system. | 分子名称: | Conserved membrane protein | 著者 | Arbing, M.A, Chan, S, Kahng, S, Kim, J, Eisenberg, D.S, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2015-07-30 | 公開日 | 2015-08-12 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | 主引用文献 | Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system. Bmc Struct.Biol., 16, 2016
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5ABH
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![BU of 5abh by Molmil](/molmil-images/mine/5abh) | Structure of GH84 with ligand | 分子名称: | 1,2-ETHANEDIOL, 2-[(2R,3S,4R,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)-1-pentyl-pyrrolidin-2-yl]-N-methyl-ethanamide, CALCIUM ION, ... | 著者 | Bergeron-Brlek, M, Goodwin-Tindall, J, Cekic, N, Varghese, V, Zandberg, W.F, Shan, X, Roth, C, Chan, S, Davies, G.J, Vocadlo, D.J, Britton, R. | 登録日 | 2015-08-05 | 公開日 | 2015-11-18 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | A Convenient Approach to Stereoisomeric Iminocyclitols: Generation of Potent Brain-Permeable Oga Inhibitors. Angew.Chem.Int.Ed.Engl., 54, 2015
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5ABE
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![BU of 5abe by Molmil](/molmil-images/mine/5abe) | Structure of GH84 with ligand | 分子名称: | 2-[(2S,3S,4R,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)-1-pentyl-pyrrolidin-2-yl]-N-methyl-ethanamide, CALCIUM ION, O-GLCNACASE BT_4395 | 著者 | Bergeron-Brlek, M, Goodwin-Tindall, J, Cekic, N, Varghese, V, Zandberg, W.F, Shan, X, Roth, C, Chan, S, Davies, G.J, Vocadlo, D.J, Britton, R. | 登録日 | 2015-08-05 | 公開日 | 2015-11-18 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A Convenient Approach to Stereoisomeric Iminocyclitols: Generation of Potent Brain-Permeable Oga Inhibitors. Angew.Chem.Int.Ed.Engl., 54, 2015
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5ABF
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![BU of 5abf by Molmil](/molmil-images/mine/5abf) | Structure of GH84 with ligand | 分子名称: | 1,2-ETHANEDIOL, 2-[(2S,3R,4R,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)-1-pentyl-pyrrolidin-2-yl]-N-methyl-ethanamide, CALCIUM ION, ... | 著者 | Bergeron-Brlek, M, Goodwin-Tindall, J, Cekic, N, Varghese, V, Zandberg, W.F, Shan, X, Roth, C, Chan, S, Davies, G.J, Vocadlo, D.J, Britton, R. | 登録日 | 2015-08-05 | 公開日 | 2015-11-18 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A Convenient Approach to Stereoisomeric Iminocyclitols: Generation of Potent Brain-Permeable Oga Inhibitors. Angew.Chem.Int.Ed.Engl., 54, 2015
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8I22
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![BU of 8i22 by Molmil](/molmil-images/mine/8i22) | Acyl-ACP synthetase structure bound to pimelic acid monoethyl ester | 分子名称: | 7-ethoxy-7-oxidanylidene-heptanoic acid, Acyl-acyl carrier protein synthetase | 著者 | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-01-13 | 公開日 | 2024-01-17 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.15 Å) | 主引用文献 | Acyl-ACP synthetase structure bound to pimelic acid monoethyl ester To Be Published
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5IAO
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![BU of 5iao by Molmil](/molmil-images/mine/5iao) | |
5M7R
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![BU of 5m7r by Molmil](/molmil-images/mine/5m7r) | Structure of human O-GlcNAc hydrolase | 分子名称: | Protein O-GlcNAcase | 著者 | Roth, C, Chan, S, Offen, W.A, Hemsworth, G.R, Willems, L.I, King, D, Varghese, V, Britton, R, Vocadlo, D.J, Davies, G.J. | 登録日 | 2016-10-28 | 公開日 | 2017-03-29 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural and functional insight into human O-GlcNAcase. Nat. Chem. Biol., 13, 2017
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5M7T
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![BU of 5m7t by Molmil](/molmil-images/mine/5m7t) | Structure of human O-GlcNAc hydrolase with PugNAc type inhibitor | 分子名称: | (5R,6R,7R,8S)-8-(ACETYLAMINO)-6,7-DIHYDROXY-5-(HYDROXYMETHYL)-N-PHENYL-1,5,6,7,8,8A-HEXAHYDROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXAMIDE, Protein O-GlcNAcase | 著者 | Roth, C, Chan, S, Offen, W.A, Hemsworth, G.R, Willems, L.I, King, D, Varghese, V, Britton, R, Vocadlo, D.J, Davies, G.J. | 登録日 | 2016-10-28 | 公開日 | 2017-03-29 | 最終更新日 | 2017-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural and functional insight into human O-GlcNAcase. Nat. Chem. Biol., 13, 2017
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5M7S
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![BU of 5m7s by Molmil](/molmil-images/mine/5m7s) | Structure of human O-GlcNAc hydrolase with bound transition state analog ThiametG | 分子名称: | (3AR,5R,6S,7R,7AR)-2-(ETHYLAMINO)-5-(HYDROXYMETHYL)-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D][1,3]THIAZOLE-6,7-DIOL, Protein O-GlcNAcase | 著者 | Roth, C, Chan, S, Offen, W.A, Hemsworth, G.R, Willems, L.I, King, D, Varghese, V, Britton, R, Vocadlo, D.J, Davies, G.J. | 登録日 | 2016-10-28 | 公開日 | 2017-03-29 | 最終更新日 | 2017-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and functional insight into human O-GlcNAcase. Nat. Chem. Biol., 13, 2017
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5M7U
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![BU of 5m7u by Molmil](/molmil-images/mine/5m7u) | Structure of human O-GlcNAc hydrolase with new iminocyclitol type inhibitor | 分子名称: | 2-[(2~{R},3~{S},4~{R},5~{R})-5-(hydroxymethyl)-3,4-bis(oxidanyl)-1-[3-[3-(trifluoromethyl)phenyl]propyl]pyrrolidin-2-yl]-~{N}-methyl-ethanamide, Protein O-GlcNAcase | 著者 | Roth, C, Chan, S, Offen, W.A, Hemsworth, G.R, Willems, L.I, King, D, Varghese, V, Britton, R, Vocadlo, D.J, Davies, G.J. | 登録日 | 2016-10-28 | 公開日 | 2017-03-29 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and functional insight into human O-GlcNAcase. Nat. Chem. Biol., 13, 2017
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3OGI
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![BU of 3ogi by Molmil](/molmil-images/mine/3ogi) | Crystal structure of the Mycobacterium tuberculosis H37Rv EsxOP complex (Rv2346c-Rv2347c) | 分子名称: | Putative ESAT-6-like protein 6, Putative ESAT-6-like protein 7 | 著者 | Arbing, M.A, Chan, S, Zhou, T.T, Ahn, C, Harris, L, Kuo, E, Sawaya, M.R, Cascio, D, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC) | 登録日 | 2010-08-16 | 公開日 | 2010-08-25 | 最終更新日 | 2014-05-21 | 実験手法 | X-RAY DIFFRACTION (2.549 Å) | 主引用文献 | Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions. Plos One, 8, 2013
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3B9Z
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![BU of 3b9z by Molmil](/molmil-images/mine/3b9z) | Crystal structure of the Nitrosomonas europaea Rh protein complexed with carbon dioxide | 分子名称: | Ammonium transporter family Rh-like protein, CARBON DIOXIDE, UNKNOWN LIGAND, ... | 著者 | Li, X, Jayachandran, S, Nguyen, H.-H.T, Chan, M.K. | 登録日 | 2007-11-07 | 公開日 | 2007-12-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure of the Nitrosomonas europaea Rh protein. Proc.Natl.Acad.Sci.Usa, 104, 2007
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3B9Y
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![BU of 3b9y by Molmil](/molmil-images/mine/3b9y) | Crystal structure of the Nitrosomonas europaea Rh protein | 分子名称: | Ammonium transporter family Rh-like protein, UNKNOWN LIGAND, octyl beta-D-glucopyranoside | 著者 | Li, X, Jayachandran, S, Nguyen, H.-H.T, Chan, M.K. | 登録日 | 2007-11-07 | 公開日 | 2007-12-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure of the Nitrosomonas europaea Rh protein. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2GM7
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![BU of 2gm7 by Molmil](/molmil-images/mine/2gm7) | TenA Homolog/Thi-4 Thiaminase from Pyrobaculum Aerophilum | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, GLYCEROL, PHOSPHATE ION, ... | 著者 | Sawaya, M.R, Chan, S, Han, G.W, Perry, L.J. | 登録日 | 2006-04-06 | 公開日 | 2006-04-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of a Ten A Homolog/Thi-4 Thiaminase from Pyrobaculum Aerophilum To be Published
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2AW9
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![BU of 2aw9 by Molmil](/molmil-images/mine/2aw9) | |
1SGV
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![BU of 1sgv by Molmil](/molmil-images/mine/1sgv) | STRUCTURE OF TRNA PSI55 PSEUDOURIDINE SYNTHASE (TRUB) | 分子名称: | tRNA pseudouridine synthase B | 著者 | Chaudhuri, B.N, Chan, S, Perry, L.J, Yeates, T.O, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2004-02-24 | 公開日 | 2004-03-02 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the apo forms of psi 55 tRNA pseudouridine synthase from Mycobacterium tuberculosis: a hinge at the base of the catalytic cleft. J.Biol.Chem., 279, 2004
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1RII
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![BU of 1rii by Molmil](/molmil-images/mine/1rii) | Crystal structure of phosphoglycerate mutase from M. Tuberculosis | 分子名称: | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, GLYCEROL | 著者 | Mueller, P, Sawaya, M.R, Chan, S, Wu, Y, Pashkova, I, Perry, J, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2003-11-17 | 公開日 | 2004-10-05 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The 1.70 angstroms X-ray crystal structure of Mycobacterium tuberculosis phosphoglycerate mutase. Acta Crystallogr.,Sect.D, 61, 2005
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4I0X
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![BU of 4i0x by Molmil](/molmil-images/mine/4i0x) | Crystal structure of the Mycobacterum abscessus EsxEF (Mab_3112-Mab_3113) complex | 分子名称: | BETA-MERCAPTOETHANOL, ESAT-6-like protein MAB_3112, ESAT-6-like protein MAB_3113, ... | 著者 | Arbing, M.A, Chan, S, Lu, J, Kuo, E, Harris, L, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC) | 登録日 | 2012-11-19 | 公開日 | 2013-01-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.956 Å) | 主引用文献 | Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions. Plos One, 8, 2013
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4GZR
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![BU of 4gzr by Molmil](/molmil-images/mine/4gzr) | Crystal structure of the Mycobacterium tuberculosis H37Rv EsxOP (Rv2346c-Rv2347c) complex in space group C2221 | 分子名称: | ESAT-6-like protein 6, ESAT-6-like protein 7, SULFATE ION | 著者 | Arbing, M.A, Chan, S, He, Q, Harris, L, Zhou, T.T, Kuo, E, Ahn, C.J, Eisenberg, D, TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI) | 登録日 | 2012-09-06 | 公開日 | 2012-09-26 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.553 Å) | 主引用文献 | Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions. Plos One, 8, 2013
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2QYG
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![BU of 2qyg by Molmil](/molmil-images/mine/2qyg) | Crystal Structure of a RuBisCO-like Protein rlp2 from Rhodopseudomonas palustris | 分子名称: | Ribulose bisphosphate carboxylase-like protein 2 | 著者 | Li, H, Chan, S, Tabita, F.R, Eisenberg, D. | 登録日 | 2007-08-14 | 公開日 | 2007-09-11 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Function, structure, and evolution of the RubisCO-like proteins and their RubisCO homologs. Microbiol.Mol.Biol.Rev., 71, 2007
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4WUY
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![BU of 4wuy by Molmil](/molmil-images/mine/4wuy) | Crystal Structure of Protein Lysine Methyltransferase SMYD2 in complex with LLY-507, a Cell-Active, Potent and Selective Inhibitor | 分子名称: | 5-cyano-2'-{4-[2-(3-methyl-1H-indol-1-yl)ethyl]piperazin-1-yl}-N-[3-(pyrrolidin-1-yl)propyl]biphenyl-3-carboxamide, GLYCEROL, N-lysine methyltransferase SMYD2, ... | 著者 | Nguyen, H, Allali-Hassani, A, Antonysamy, S, Chang, S, Chen, L.H, Curtis, C, Emtage, S, Fan, L, Gheyi, T, Li, F, Liu, S, Martin, J.R, Mendel, D, Olsen, J.B, Pelletier, L, Shatseva, T, Wu, S, Zhang, F.F, Arrowsmith, C.H, Brown, P.J, Campbell, R.M, Garcia, B.A, Barsyte-Lovejoy, D, Mader, M, Vedadi, M. | 登録日 | 2014-11-04 | 公開日 | 2015-04-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2. J.Biol.Chem., 290, 2015
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1ET1
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![BU of 1et1 by Molmil](/molmil-images/mine/1et1) | CRYSTAL STRUCTURE OF HUMAN PARATHYROID HORMONE 1-34 AT 0.9 A RESOLUTION | 分子名称: | PARATHYROID HORMONE, SODIUM ION | 著者 | Jin, L, Briggs, S.L, Chandrasekhar, S, Chirgadze, N.Y, Clawson, D.K, Schevitz, R.W, Smiley, D.L, Tashjian, A.H, Zhang, F. | 登録日 | 2000-04-12 | 公開日 | 2000-09-06 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (0.9 Å) | 主引用文献 | Crystal structure of human parathyroid hormone 1-34 at 0.9-A resolution. J.Biol.Chem., 275, 2000
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