5M7R

Structure of human O-GlcNAc hydrolase

Summary for 5M7R

DescriptorProtein O-GlcNAcase (2 entities in total)
Functional Keywordshuman glacoside hydrolase glcnac, hydrolase
Biological sourceHomo sapiens (Human)
Cellular locationIsoform 3: Nucleus . Isoform 1: Cytoplasm  O60502
Total number of polymer chains2
Total molecular weight206041.81
Authors
Roth, C.,Chan, S.,Offen, W.A.,Hemsworth, G.R.,Willems, L.I.,King, D.,Varghese, V.,Britton, R.,Vocadlo, D.J.,Davies, G.J. (deposition date: 2016-10-28, release date: 2017-03-29, Last modification date: 2017-08-30)
Primary citation
Roth, C.,Chan, S.,Offen, W.A.,Hemsworth, G.R.,Willems, L.I.,King, D.T.,Varghese, V.,Britton, R.,Vocadlo, D.J.,Davies, G.J.
Structural and functional insight into human O-GlcNAcase.
Nat. Chem. Biol., 13:610-612, 2017
PubMed: 28346405 (PDB entries with the same primary citation)
DOI: 10.1038/nchembio.2358
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.35 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25020.4%5.7%3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5m7r
no rotation
Molmil generated image of 5m7r
rotated about x axis by 90°
Molmil generated image of 5m7r
rotated about y axis by 90°