5M7R

Structure of human O-GlcNAc hydrolase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004415	molecular_function	hyalurononglucosaminidase activity
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006044	biological_process	N-acetylglucosamine metabolic process
A	0006493	biological_process	protein O-linked glycosylation
A	0006516	biological_process	glycoprotein catabolic process
A	0006517	biological_process	protein deglycosylation
A	0009100	biological_process	glycoprotein metabolic process
A	0015929	molecular_function	hexosaminidase activity
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0042802	molecular_function	identical protein binding
A	0102571	molecular_function	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity
A	0140096	molecular_function	catalytic activity, acting on a protein
B	0004415	molecular_function	hyalurononglucosaminidase activity
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006044	biological_process	N-acetylglucosamine metabolic process
B	0006493	biological_process	protein O-linked glycosylation
B	0006516	biological_process	glycoprotein catabolic process
B	0006517	biological_process	protein deglycosylation
B	0009100	biological_process	glycoprotein metabolic process
B	0015929	molecular_function	hexosaminidase activity
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0042802	molecular_function	identical protein binding
B	0102571	molecular_function	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity
B	0140096	molecular_function	catalytic activity, acting on a protein

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	552
Details	Domain: {"description":"GH84","evidences":[{"source":"PROSITE-ProRule","id":"PRU01353","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PROSITE-ProRule","id":"PRU01353","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16533067","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28939839","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5VVT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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