Crystal structure of the Mycobacterium tuberculosis H37Rv EsxOP (Rv2346c-Rv2347c) complex in space group C2221

Summary for 4GZR

DescriptorESAT-6-like protein 6, ESAT-6-like protein 7, SULFATE ION, ... (4 entities in total)
Functional Keywordswxg100, structural genomics, tb structural genomics consortium, tbsgc, integrated center for structure and function innovation, isfi, unknown function, secreted, psi-2, protein structure initiative
Biological sourceMycobacterium tuberculosis
Total number of polymer chains4
Total molecular weight44028.5
Primary citation
Arbing, M.A.,Chan, S.,Harris, L.,Kuo, E.,Zhou, T.T.,Ahn, C.J.,Nguyen, L.,He, Q.,Lu, J.,Menchavez, P.T.,Shin, A.,Holton, T.,Sawaya, M.R.,Cascio, D.,Eisenberg, D.
Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions.
Plos One, 8:e81753-e81753, 2013
PubMed: 24312350 (PDB entries with the same primary citation)
DOI: 10.1371/journal.pone.0081753
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.23230 1.4% 13.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-23