3PS8
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![BU of 3ps8 by Molmil](/molmil-images/mine/3ps8) | Crystal structure of L68V mutant of human cystatin C | 分子名称: | ACETATE ION, Cystatin-C, DI(HYDROXYETHYL)ETHER | 著者 | Orlikowska, M, Borek, D, Otwinowski, Z, Skowron, P, Szymanska, A. | 登録日 | 2010-12-01 | 公開日 | 2011-12-21 | 最終更新日 | 2013-04-03 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Crystal structure of L68V mutant of human cystatin C To be Published
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3QRD
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![BU of 3qrd by Molmil](/molmil-images/mine/3qrd) | Crystal structure of L68V mutant of human cystatin C | 分子名称: | Cystatin-C, DI(HYDROXYETHYL)ETHER | 著者 | Orlikowska, M, Borek, D, Otwinowski, Z, Skowron, P, Szymanska, A. | 登録日 | 2011-02-17 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Crystal structure of L68V mutant of human cystatin C To be Published
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3OAM
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![BU of 3oam by Molmil](/molmil-images/mine/3oam) | Crystal structure of cytidylyltransferase from Vibrio cholerae | 分子名称: | 3-deoxy-manno-octulosonate cytidylyltransferase, SODIUM ION | 著者 | Hattne, J, Borek, D, Grimshaw, S, Nakka, C, Rostankowski, R, Otwinowski, Z, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-08-05 | 公開日 | 2010-09-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structure of cytidylyltransferase from Vibrio cholerae TO BE PUBLISHED
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3RV5
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![BU of 3rv5 by Molmil](/molmil-images/mine/3rv5) | Crystal structure of human cardiac troponin C regulatory domain in complex with cadmium and deoxycholic acid | 分子名称: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, CADMIUM ION, CALCIUM ION, ... | 著者 | Li, A.Y, Lee, J, Borek, D, Otwinowski, Z, Tibbits, G, Paetzel, M. | 登録日 | 2011-05-06 | 公開日 | 2011-08-31 | 最終更新日 | 2011-11-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of cardiac troponin C regulatory domain in complex with cadmium and deoxycholic Acid reveals novel conformation. J.Mol.Biol., 413, 2011
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4OFK
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![BU of 4ofk by Molmil](/molmil-images/mine/4ofk) | Crystal Structure of SYG-2 D4 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Ozkan, E, Borek, D, Otwinowski, Z, Garcia, K.C. | 登録日 | 2014-01-15 | 公開日 | 2014-02-19 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | 主引用文献 | Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis. Cell(Cambridge,Mass.), 156, 2014
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5TVL
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![BU of 5tvl by Molmil](/molmil-images/mine/5tvl) | Crystal structure of foldase protein PrsA from Streptococcus pneumoniae str. Canada MDR_19A | 分子名称: | CHLORIDE ION, Foldase protein PrsA, GLYCEROL, ... | 著者 | Borek, D, Yim, V, Kudritska, M, Wawrzak, Z, Stogios, P.J, Otwinowski, Z, Savchenko, A, Anderson, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-11-09 | 公開日 | 2016-11-23 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Crystal structure of foldase protein PrsA from Streptococcus pneumoniae str. Canada MDR_19A To Be Published
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6M7Z
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![BU of 6m7z by Molmil](/molmil-images/mine/6m7z) | A divergent kinase lacking the glycine-rich loop regulates membrane ultrastructure of the Toxoplasma parasitophorous vacuole | 分子名称: | 1,2-ETHANEDIOL, Bradyzoite pseudokinase 1, CHLORIDE ION | 著者 | Beraki, T, Borek, D.M, Reese, M.L. | 登録日 | 2018-08-21 | 公開日 | 2018-10-17 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Divergent kinase regulates membrane ultrastructure of theToxoplasmaparasitophorous vacuole. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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4U2X
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![BU of 4u2x by Molmil](/molmil-images/mine/4u2x) | Ebola virus VP24 in complex with Karyopherin alpha 5 C-terminus | 分子名称: | CHLORIDE ION, Importin subunit alpha-6, Membrane-associated protein VP24 | 著者 | Xu, W, Leung, D, Borek, D, Amarasinghe, G. | 登録日 | 2014-07-18 | 公開日 | 2014-08-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.153 Å) | 主引用文献 | Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1. Cell Host Microbe, 16, 2014
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4YPI
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![BU of 4ypi by Molmil](/molmil-images/mine/4ypi) | Structure of Ebola virus nucleoprotein N-terminal fragment bound to a peptide derived from Ebola VP35 | 分子名称: | Nucleoprotein, Polymerase cofactor VP35 | 著者 | Leung, D.W, Borek, D.M, Binning, J.M, Otwinowski, Z, Amarasinghe, G.K, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2015-03-13 | 公開日 | 2015-04-08 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (3.71 Å) | 主引用文献 | An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions. Cell Rep, 11, 2015
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2ZAK
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![BU of 2zak by Molmil](/molmil-images/mine/2zak) | Orthorhombic crystal structure of precursor E. coli isoaspartyl peptidase/L-asparaginase (EcAIII) with active-site T179A mutation | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, L-asparaginase precursor, ... | 著者 | Michalska, K, Hernandez-Santoyo, A, Jaskolski, M. | 登録日 | 2007-10-07 | 公開日 | 2008-03-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Crystal packing of plant-type L-asparaginase from Escherichia coli Acta Crystallogr.,Sect.D, 64, 2008
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3C17
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![BU of 3c17 by Molmil](/molmil-images/mine/3c17) | |
2GEZ
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![BU of 2gez by Molmil](/molmil-images/mine/2gez) | Crystal structure of potassium-independent plant asparaginase | 分子名称: | CHLORIDE ION, L-asparaginase alpha subunit, L-asparaginase beta subunit, ... | 著者 | Michalska, K, Bujacz, G, Jaskolski, M. | 登録日 | 2006-03-21 | 公開日 | 2006-07-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of plant asparaginase. J.Mol.Biol., 360, 2006
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4IJF
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![BU of 4ijf by Molmil](/molmil-images/mine/4ijf) | Crystal structure of the Zaire ebolavirus VP35 interferon inhibitory domain K222A/R225A/K248A/K251A mutant | 分子名称: | Polymerase cofactor VP35 | 著者 | Binning, J.B, Wang, T, Leung, D.W, Xu, W, Borek, D, Amarasinghe, G.K. | 登録日 | 2012-12-21 | 公開日 | 2013-10-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.506 Å) | 主引用文献 | Development of RNA Aptamers Targeting Ebola Virus VP35. Biochemistry, 52, 2013
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4IJE
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![BU of 4ije by Molmil](/molmil-images/mine/4ije) | Crystal structure of the Zaire ebolavirus VP35 interferon inhibitory domain R312A/K319A/R322A mutant | 分子名称: | PHOSPHATE ION, POTASSIUM ION, Polymerase cofactor VP35, ... | 著者 | Binning, J.B, Wang, T, Leung, D.W, Xu, W, Borek, D, Amarasinghe, G.K. | 登録日 | 2012-12-21 | 公開日 | 2013-10-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.899 Å) | 主引用文献 | Development of RNA Aptamers Targeting Ebola Virus VP35. Biochemistry, 52, 2013
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7ROA
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![BU of 7roa by Molmil](/molmil-images/mine/7roa) | Crystal structure of EntV136 from Enterococcus faecalis | 分子名称: | EntV | 著者 | Stogios, P.J, Evdokimova, E, Kim, Y, Garsin, D, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2021-07-30 | 公開日 | 2022-10-12 | 最終更新日 | 2023-01-25 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Structural and functional analysis of EntV reveals a 12 amino acid fragment protective against fungal infections. Nat Commun, 13, 2022
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4PV3
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![BU of 4pv3 by Molmil](/molmil-images/mine/4pv3) | Crystal structure of potassium-dependent plant-type L-asparaginase from Phaseolus vulgaris in complex with Na+ cations | 分子名称: | L-ASPARAGINASE ALPHA SUBUNIT, L-ASPARAGINASE BETA SUBUNIT, SODIUM ION | 著者 | Bejger, M, Gilski, M, Imiolczyk, B, Jaskolski, M. | 登録日 | 2014-03-14 | 公開日 | 2014-09-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Na+/K+ exchange switches the catalytic apparatus of potassium-dependent plant L-asparaginase Acta Crystallogr.,Sect.D, 70, 2014
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4PV2
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![BU of 4pv2 by Molmil](/molmil-images/mine/4pv2) | Crystal structure of potassium-dependent plant-type L-asparaginase from Phaseolus vulgaris in complex with K+ and Na+ cations | 分子名称: | L-ASPARAGINASE ALPHA SUBUNIT, L-ASPARAGINASE BETA SUBUNIT, NITRATE ION, ... | 著者 | Bejger, M, Gilski, M, Imiolczyk, B, Clavel, D, Jaskolski, M. | 登録日 | 2014-03-14 | 公開日 | 2014-09-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Na+/K+ exchange switches the catalytic apparatus of potassium-dependent plant L-asparaginase Acta Crystallogr.,Sect.D, 70, 2014
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4PU6
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![BU of 4pu6 by Molmil](/molmil-images/mine/4pu6) | Crystal structure of potassium-dependent plant-type L-asparaginase from Phaseolus vulgaris in complex with K+ cations | 分子名称: | ASPARTIC ACID, L-ASPARAGINASE ALPHA SUBUNIT, L-ASPARAGINASE BETA SUBUNIT, ... | 著者 | Bejger, M, Gilski, M, Imiolczyk, B, Jaskolski, M. | 登録日 | 2014-03-12 | 公開日 | 2014-09-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Na+/K+ exchange switches the catalytic apparatus of potassium-dependent plant L-asparaginase Acta Crystallogr.,Sect.D, 70, 2014
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7TBU
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![BU of 7tbu by Molmil](/molmil-images/mine/7tbu) | Crystal structure of the 5-enolpyruvate-shikimate-3-phosphate synthase (EPSPS) domain of Aro1 from Candida albicans in complex with shikimate-3-phosphate | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-enolpyruvylshikimate-3-phosphate synthase, SHIKIMATE-3-PHOSPHATE | 著者 | Stogios, P.J, Evdokimova, E, Michalska, K, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-12-22 | 公開日 | 2022-03-16 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in Candida albicans. Life Sci Alliance, 5, 2022
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7TBV
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![BU of 7tbv by Molmil](/molmil-images/mine/7tbv) | Crystal structure of the shikimate kinase + 3-dehydroquinate dehydratase + 3-dehydroshikimate dehydrogenase domains of Aro1 from Candida albicans | 分子名称: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | 著者 | Stogios, P.J, Evdokimova, E, Michalska, K, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-12-22 | 公開日 | 2022-03-16 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in Candida albicans. Life Sci Alliance, 5, 2022
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2F2L
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![BU of 2f2l by Molmil](/molmil-images/mine/2f2l) | |
5T8V
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![BU of 5t8v by Molmil](/molmil-images/mine/5t8v) | Chaetomium thermophilum cohesin loader SCC2, C-terminal fragment | 分子名称: | CITRIC ACID, Putative uncharacterized protein | 著者 | Tomchick, D.R, Yu, H, Kikuchi, S, Ouyang, Z, Borek, D, Otwinowski, Z. | 登録日 | 2016-09-08 | 公開日 | 2016-10-19 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.798 Å) | 主引用文献 | Crystal structure of the cohesin loader Scc2 and insight into cohesinopathy. Proc.Natl.Acad.Sci.USA, 113, 2016
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4TOR
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![BU of 4tor by Molmil](/molmil-images/mine/4tor) | Crystal structure of Tankyrase 1 with IWR-8 | 分子名称: | 1-[(1-acetyl-5-bromo-1H-indol-6-yl)sulfonyl]-N-ethyl-N-(3-methylphenyl)piperidine-4-carboxamide, CHLORIDE ION, Tankyrase-1, ... | 著者 | Chen, H, Zhang, X, Lum, L, Chen, C. | 登録日 | 2014-06-06 | 公開日 | 2015-05-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | 主引用文献 | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells. Mol.Cell.Biol., 35, 2015
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4TOS
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![BU of 4tos by Molmil](/molmil-images/mine/4tos) | Crystal structure of Tankyrase 1 with 355 | 分子名称: | Tankyrase-1, ZINC ION, trans-N-benzyl-4-({1-[(6-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)methyl]-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl}methyl)cyclohexanecarboxamide | 著者 | Chen, H, Zhang, X, Lum, l, Chen, C. | 登録日 | 2014-06-06 | 公開日 | 2015-05-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | 主引用文献 | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells. Mol.Cell.Biol., 35, 2015
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6C5C
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![BU of 6c5c by Molmil](/molmil-images/mine/6c5c) | Crystal structure of the 3-dehydroquinate synthase (DHQS) domain of Aro1 from Candida albicans SC5314 in complex with NADH | 分子名称: | 1,2-ETHANEDIOL, 3-dehydroquinate synthase, CHLORIDE ION, ... | 著者 | Michalska, K, Evdokimova, E, Di Leo, R, Stogios, P.J, Savchenko, A, Joachimiak, A, Satchell, K, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-01-16 | 公開日 | 2018-01-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in Candida albicans. Life Sci Alliance, 5, 2022
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