4IJF
Crystal structure of the Zaire ebolavirus VP35 interferon inhibitory domain K222A/R225A/K248A/K251A mutant
Summary for 4IJF
| Entry DOI | 10.2210/pdb4ijf/pdb |
| Related | 3FKE 4IJE |
| Descriptor | Polymerase cofactor VP35 (2 entities in total) |
| Functional Keywords | ifn inhibition, polymerase cofactor, rna binding protein, interferon antagonism, dsrna, virus, viral protein |
| Biological source | Zaire ebolavirus (ZEBOV) |
| Cellular location | Virion: Q05127 |
| Total number of polymer chains | 1 |
| Total formula weight | 13852.99 |
| Authors | Binning, J.B.,Wang, T.,Leung, D.W.,Xu, W.,Borek, D.,Amarasinghe, G.K. (deposition date: 2012-12-21, release date: 2013-10-09, Last modification date: 2023-09-20) |
| Primary citation | Binning, J.M.,Wang, T.,Luthra, P.,Shabman, R.S.,Borek, D.M.,Liu, G.,Xu, W.,Leung, D.W.,Basler, C.F.,Amarasinghe, G.K. Development of RNA Aptamers Targeting Ebola Virus VP35. Biochemistry, 52:8406-8419, 2013 Cited by PubMed: 24067086DOI: 10.1021/bi400704d PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.506 Å) |
Structure validation
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