4IJF
Crystal structure of the Zaire ebolavirus VP35 interferon inhibitory domain K222A/R225A/K248A/K251A mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Polymerase cofactor VP35 | polymer | 128 | 13853.0 | 1 | UniProt (Q05127) Pfam (PF02097) | Zaire ebolavirus (ZEBOV) | |
| 2 | B (A) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A: 218 - 340 (UniProt: Q05127)
| PDB | External Database | Details |
|---|---|---|
| Gly 213 | - | expression tag |
| His 214 | - | expression tag |
| Met 215 | - | expression tag |
| Gly 216 | - | expression tag |
| Lys 217 | - | expression tag |
| Ala 222 | Lys 222 | engineered mutation |
| Ala 225 | Arg 225 | engineered mutation |
| Ala 248 | Lys 248 | engineered mutation |
| Ala 251 | Lys 251 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13853.0 | |
| All* | Total formula weight | 13853.0 |
