4IJE

Crystal structure of the Zaire ebolavirus VP35 interferon inhibitory domain R312A/K319A/R322A mutant

Summary for 4IJE

Entry DOI	10.2210/pdb4ije/pdb
Related	3FKE 3L25 3L26 3L27 3L28 3L29 4IJF
Descriptor	Polymerase cofactor VP35, SODIUM ION, POTASSIUM ION, ... (5 entities in total)
Functional Keywords	ifn inhibition, polymerase cofactor, rna binding protein, interferon antagonism, virus, viral protein
Biological source	Zaire ebolavirus (ZEBOV)
Cellular location	Virion: Q05127
Total number of polymer chains	4
Total formula weight	56359.71
Authors	Binning, J.B.,Wang, T.,Leung, D.W.,Xu, W.,Borek, D.,Amarasinghe, G.K. (deposition date: 2012-12-21, release date: 2013-10-09, Last modification date: 2023-09-20)
Primary citation	Binning, J.M.,Wang, T.,Luthra, P.,Shabman, R.S.,Borek, D.M.,Liu, G.,Xu, W.,Leung, D.W.,Basler, C.F.,Amarasinghe, G.K. Development of RNA Aptamers Targeting Ebola Virus VP35. Biochemistry, 52:8406-8419, 2013 Cited by PubMed: 24067086 DOI: 10.1021/bi400704d PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.899 Å)

Structure validation