4IJE
Crystal structure of the Zaire ebolavirus VP35 interferon inhibitory domain R312A/K319A/R322A mutant
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Polymerase cofactor VP35 | polymer | 129 | 13980.2 | 4 | UniProt (Q05127) Pfam (PF02097) In PDB | Zaire ebolavirus (ZEBOV) | |
2 | A, B, D | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) | |||
3 | A | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
4 | B, C, D | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
5 | water | water | 18.0 | 351 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 218 - 340 (UniProt: Q05127)
PDB | External Database | Details |
---|---|---|
Gly 212 | - | expression tag |
His 213 | - | expression tag |
Met 214 | - | expression tag |
Gly 215 | - | expression tag |
Lys 216 | - | expression tag |
Pro 217 | - | expression tag |
Ala 312 | Arg 312 | engineered mutation |
Ala 319 | Lys 319 | engineered mutation |
Ala 322 | Arg 322 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 55920.8 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 439.0 | |
All* | Total formula weight | 56359.7 |