4IJE
Crystal structure of the Zaire ebolavirus VP35 interferon inhibitory domain R312A/K319A/R322A mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Polymerase cofactor VP35 | polymer | 129 | 13980.2 | 4 | UniProt (Q05127) Pfam (PF02097) | Zaire ebolavirus (ZEBOV) | |
| 2 | E, G, H, K, L (A, B, D) | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) | |||
| 3 | F (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 4 | I, J, M (B, C, D) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 5 | N, O, P, Q (A, B, C, D) | water | water | 18.0 | 351 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 218 - 340 (UniProt: Q05127)
| PDB | External Database | Details |
|---|---|---|
| Gly 212 | - | expression tag |
| His 213 | - | expression tag |
| Met 214 | - | expression tag |
| Gly 215 | - | expression tag |
| Lys 216 | - | expression tag |
| Pro 217 | - | expression tag |
| Ala 312 | Arg 312 | engineered mutation |
| Ala 319 | Lys 319 | engineered mutation |
| Ala 322 | Arg 322 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 55920.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 439.0 | |
| All* | Total formula weight | 56359.7 |
