4IJE
Crystal structure of the Zaire ebolavirus VP35 interferon inhibitory domain R312A/K319A/R322A mutant
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA A 401 |
| Chain | Residue |
| A | PRO233 |
| A | THR237 |
| A | HOH509 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE K A 402 |
| Chain | Residue |
| C | GLY234 |
| A | LEU232 |
| A | PRO233 |
| A | GLY234 |
| A | HOH503 |
| A | HOH583 |
| C | LEU232 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA B 401 |
| Chain | Residue |
| B | PRO233 |
| B | THR237 |
| B | HOH507 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 402 |
| Chain | Residue |
| B | PRO315 |
| B | PRO316 |
| B | HOH547 |
| C | PRO315 |
| C | PRO316 |
| C | HOH537 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 B 403 |
| Chain | Residue |
| B | ILE227 |
| B | HIS231 |
| B | GLN264 |
| B | HOH565 |
| B | HOH580 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 C 401 |
| Chain | Residue |
| C | ILE227 |
| C | HIS231 |
| C | GLN264 |
| C | HOH583 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NA D 401 |
| Chain | Residue |
| B | GLY234 |
| D | TYR229 |
| D | LEU232 |
| D | GLY234 |
| D | HIS240 |
| D | HOH586 |
| D | HOH590 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA D 402 |
| Chain | Residue |
| D | PRO233 |
| D | THR237 |
| D | HOH507 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 D 403 |
| Chain | Residue |
| D | ILE227 |
| D | HIS231 |
| D | GLN264 |
| D | HOH534 |
| D | HOH545 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine; by host","evidences":[{"source":"PubMed","id":"31562565","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine; by host","evidences":[{"source":"PubMed","id":"31562565","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31694758","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"28679761","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35533195","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
