7X2M
 
 | | Crystal structure of nanobody 1-2C7 with SARS-CoV-2 RBD | | 分子名称: | 1-2C7, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-D-mannopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1 | | 著者 | Wang, X.Q, Zhang, L.Q, Ren, Y.F, Li, M.X. | | 登録日 | 2022-02-25 | | 公開日 | 2022-12-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses.
Nat Commun, 13, 2022
|
|
7X2J
 | | Crystal structure of nanobody Nb70 with SARS-CoV RBD | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Nb70, Spike protein S1 | | 著者 | Wang, X.Q, Zhang, L.Q, Ren, Y.F, Li, M.X. | | 登録日 | 2022-02-25 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-06-28 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses.
Nat Commun, 13, 2022
|
|
7X2K
 | | Crystal structure of nanobody Nb70 with antibody 1F11 fab and SARS-CoV-2 RBD | | 分子名称: | 1F11-H, 1F11-L, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wang, X.Q, Zhang, L.Q, Ren, Y.F, Li, M.X. | | 登録日 | 2022-02-25 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-06-28 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses.
Nat Commun, 13, 2022
|
|
7X2L
 | | Crystal structure of nanobody 3-2A2-4 with SARS-CoV-2 RBD | | 分子名称: | Nanobody 3-2A2-4, Spike protein S1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Wang, X.Q, Zhang, L.Q, Ren, Y.F, Li, M.X. | | 登録日 | 2022-02-25 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses.
Nat Commun, 13, 2022
|
|
5H3X
 | |
5GGZ
 | | Crystal structure of novel inhibitor bound with Hsp90 | | 分子名称: | Heat shock protein HSP 90-alpha, [2,4-bis(oxidanyl)-5-propan-2-yl-phenyl]-(2-ethoxy-7,8-dihydro-5~{H}-pyrido[4,3-d]pyrimidin-6-yl)methanone | | 著者 | Chen, T.T, Li, J, Xu, Y.C. | | 登録日 | 2016-06-16 | | 公開日 | 2017-03-08 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.015 Å) | | 主引用文献 | Novel Tetrahydropyrido[4,3-d]pyrimidines as Potent Inhibitors of Chaperone Heat Shock Protein 90
J. Med. Chem., 59, 2016
|
|
5EM4
 | | Structure of CYP2B4 F244W in a ligand free conformation | | 分子名称: | 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Shah, M.B, Stout, C.D, Halpert, J.R. | | 登録日 | 2015-11-05 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | | 主引用文献 | Coumarin Derivatives as Substrate Probes of Mammalian Cytochromes P450 2B4 and 2B6: Assessing the Importance of 7-Alkoxy Chain Length, Halogen Substitution, and Non-Active Site Mutations.
Biochemistry, 55, 2016
|
|
2M2J
 | | Solution NMR structure of the N-terminal domain of STM1478 from Salmonella typhimurium LT2: Target STR147A of the Northeast Structural Genomics consortium (NESG), and APC101565 of the Midwest Center for Structural Genomics (MCSG). | | 分子名称: | Putative periplasmic protein | | 著者 | Houliston, S, Yee, A, Lemak, A, Garcia, M, Wu, B, Savchenko, A, Montelione, G.T, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG), Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2012-12-21 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural and Functional Characterization of DUF1471 Domains of Salmonella Proteins SrfN, YdgH/SssB, and YahO.
Plos One, 9, 2014
|
|
7CJF
 | | Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody heavy chain, ... | | 著者 | Guo, Y, Li, X, Zhang, G, Fu, D, Schweizer, L, Zhang, H, Rao, Z. | | 登録日 | 2020-07-10 | | 公開日 | 2020-11-11 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.108 Å) | | 主引用文献 | A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes.
Nat Commun, 12, 2021
|
|
7E8M
 | | Crystal structure of SARS-CoV-2 antibody P2C-1F11 with mutated RBD | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P2C-1F11 heavy chain, ... | | 著者 | Wang, X.Q, Zhang, L.Q, Ge, J.W, Wang, R.K, Lan, J. | | 登録日 | 2021-03-02 | | 公開日 | 2021-05-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species.
Immunity, 54, 2021
|
|
6MNL
 | |
8VZ7
 | |
8VX0
 | | CRYSTAL STRUCTURE OF CYP2C9*14 IN COMPLEX WITH LOSARTAN | | 分子名称: | Cytochrome P450 2C9, PHOSPHATE ION, POTASSIUM ION, ... | | 著者 | Shah, M.B. | | 登録日 | 2024-02-02 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structural and biophysical analysis of cytochrome P450 2C9*14 and *27 variants in complex with losartan.
J.Inorg.Biochem., 258, 2024
|
|
7CZ6
 | |
7D0L
 | | The major capsid of Omono River virus (strain:LZ), protrusion-free status. | | 分子名称: | Capsid protein | | 著者 | Shao, Q, Jia, X, Gao, Y, Liu, Z. | | 登録日 | 2020-09-11 | | 公開日 | 2021-03-03 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | Cryo-EM reveals a previously unrecognized structural protein of a dsRNA virus implicated in its extracellular transmission.
Plos Pathog., 17, 2021
|
|
7D0K
 | |
7V26
 | | XG005-bound SARS-CoV-2 S | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, XG005 Heavy chain, ... | | 著者 | Zhan, W.Q, Zhang, X, Sun, L, Chen, Z.G. | | 登録日 | 2021-08-07 | | 公開日 | 2021-10-20 | | 最終更新日 | 2022-07-06 | | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | | 主引用文献 | An ultrapotent pan-beta-coronavirus lineage B ( beta-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope.
Protein Cell, 13, 2022
|
|
7D3Y
 | | Crystal structure of the osPHR2-osSPX2 complex | | 分子名称: | INOSITOL HEXAKISPHOSPHATE, Protein PHOSPHATE STARVATION RESPONSE 2, SPX domain-containing protein 2,Isoform 1 of Core histone macro-H2A.1 | | 著者 | Zhang, Q.X, Guan, Z.Y, Zuo, J.Q, Zhang, Z.F, Liu, Z. | | 登録日 | 2020-09-21 | | 公開日 | 2021-10-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | Mechanistic insights into the regulation of plant phosphate homeostasis by the rice SPX2 - PHR2 complex.
Nat Commun, 13, 2022
|
|
7XMS
 | | CryoEM structure of somatostatin receptor 4 (SSTR4) in complex with Gi1 and its endogeneous ligand SST-14 | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Wenli, Z, Shuo, H, Na, Q, Wenbo, Z, Mengjie, L, Dehua, Y, Ming-Wei, W, Wu, B, Zhao, Q. | | 登録日 | 2022-04-26 | | 公開日 | 2022-08-03 | | 最終更新日 | 2022-08-17 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural insights into ligand recognition and selectivity of somatostatin receptors.
Cell Res., 32, 2022
|
|
7XMR
 | | CryoEM structure of the somatostatin receptor 2 (SSTR2) in complex with Gi1 and its endogeneous peptide ligand SST-14 | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Wenli, Z, Shuo, H, Na, Q, Wenbo, Z, Mengjie, L, Dehua, Y, Ming-Wei, W, Wu, B, Zhao, Q. | | 登録日 | 2022-04-26 | | 公開日 | 2022-08-03 | | 最終更新日 | 2022-08-17 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural insights into ligand recognition and selectivity of somatostatin receptors.
Cell Res., 32, 2022
|
|
7XMT
 | | CryoEM structure of somatostatin receptor 4 (SSTR4) with Gi1 and J-2156 | | 分子名称: | (2~{S})-2-[[(2~{S})-4-azanyl-2-[(4-methylnaphthalen-1-yl)sulfonylamino]butanoyl]amino]-3-phenyl-propanimidic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Wenli, Z, Shuo, H, Na, Q, Wenbo, Z, Mengjie, L, Dehua, Y, Ming-Wei, W, Wu, B, Zhao, Q. | | 登録日 | 2022-04-26 | | 公開日 | 2022-08-03 | | 最終更新日 | 2022-08-17 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural insights into ligand recognition and selectivity of somatostatin receptors.
Cell Res., 32, 2022
|
|
7CDI
 | | Crystal structure of SARS-CoV-2 antibody P2C-1F11 with RBD | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P2C-1F11 heavy chain, ... | | 著者 | Wang, X, Zhang, L, Ge, J, Wang, R. | | 登録日 | 2020-06-19 | | 公開日 | 2020-11-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | | 主引用文献 | Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry.
Nat Commun, 12, 2021
|
|
7CDJ
 | | Crystal structure of SARS-CoV-2 antibody P2C-1A3 with RBD | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P2C-1A3 heavy chain, ... | | 著者 | Wang, X, Zhang, L, Ge, J, Wang, R. | | 登録日 | 2020-06-19 | | 公開日 | 2020-11-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.396 Å) | | 主引用文献 | Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry.
Nat Commun, 12, 2021
|
|
7V2A
 | | SARS-CoV-2 Spike trimer in complex with XG014 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, The heavy chain of XG014, ... | | 著者 | Wang, K, Wang, X, Pan, L. | | 登録日 | 2021-08-07 | | 公開日 | 2021-10-20 | | 最終更新日 | 2022-07-06 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | An ultrapotent pan-beta-coronavirus lineage B ( beta-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope.
Protein Cell, 13, 2022
|
|
8JZ4
 | | Crystal structure of AetF in complex with FAD and 5-bromo-L-tryptophan | | 分子名称: | 5-bromo-L-tryptophan, AetF, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Li, H, Dai, L, Chen, C.-C, Guo, R.-T. | | 登録日 | 2023-07-04 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Structural and functional insights into the self-sufficient flavin-dependent halogenase.
Int.J.Biol.Macromol., 260, 2024
|
|
