7V2A

SARS-CoV-2 Spike trimer in complex with XG014 Fab

Summary for 7V2A

• Entry DOI: 10.2210/pdb7v2a/pdb
• EMDB information: 31639
• Descriptor: Spike glycoprotein, The light chain of XG014 Fab, The heavy chain of XG014, ... (4 entities in total)
• Functional Keywords: a neutralizing antibody bound with the s protein of sars-cov-2, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 9
• Total formula weight: 552158.74

Authors

Wang, K.,Wang, X.,Pan, L. (deposition date: 2021-08-07, release date: 2021-10-20, Last modification date: 2022-07-06)

• Primary citation: Liu, Z.,Xu, W.,Chen, Z.,Fu, W.,Zhan, W.,Gao, Y.,Zhou, J.,Zhou, Y.,Wu, J.,Wang, Q.,Zhang, X.,Hao, A.,Wu, W.,Zhang, Q.,Li, Y.,Fan, K.,Chen, R.,Jiang, Q.,Mayer, C.T.,Schoofs, T.,Xie, Y.,Jiang, S.,Wen, Y.,Yuan, Z.,Wang, K.,Lu, L.,Sun, L.,Wang, Q.; An ultrapotent pan-beta-coronavirus lineage B ( beta-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope.; Protein Cell, 13:655-675, 2022; PubMed: 34554412; DOI: 10.1007/s13238-021-00871-6

Experimental method

ELECTRON MICROSCOPY (3.4 Å)