5EM4
Structure of CYP2B4 F244W in a ligand free conformation
Summary for 5EM4
Entry DOI | 10.2210/pdb5em4/pdb |
Related | 1PO5 1SUO 2BDM 2Q6N 3G5N 3G93 3KW4 3ME6 3MVR 3R1A 3R1B 3TK3 3TMZ 3UAS 4H1N 4JLT |
Descriptor | Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, ... (4 entities in total) |
Functional Keywords | cytochrome p450, monooxygenase, oxidoreductase |
Biological source | Oryctolagus cuniculus (Rabbit) |
Total number of polymer chains | 2 |
Total formula weight | 115109.98 |
Authors | Shah, M.B.,Stout, C.D.,Halpert, J.R. (deposition date: 2015-11-05, release date: 2016-03-23, Last modification date: 2023-09-27) |
Primary citation | Liu, J.,Shah, M.B.,Zhang, Q.,Stout, C.D.,Halpert, J.R.,Wilderman, P.R. Coumarin Derivatives as Substrate Probes of Mammalian Cytochromes P450 2B4 and 2B6: Assessing the Importance of 7-Alkoxy Chain Length, Halogen Substitution, and Non-Active Site Mutations. Biochemistry, 55:1997-2007, 2016 Cited by PubMed: 26982502DOI: 10.1021/acs.biochem.5b01330 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.02 Å) |
Structure validation
Download full validation report