5EM4
Structure of CYP2B4 F244W in a ligand free conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cytochrome P450 2B4 | polymer | 492 | 55949.4 | 2 | UniProt (P00178) Pfam (PF00067) | Oryctolagus cuniculus (Rabbit) | CYPIIB4,Cytochrome P450 isozyme 2,Cytochrome P450 LM2,Cytochrome P450 type B0,Cytochrome P450 type B1 |
| 2 | C, F (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | D, E, G, H (A, B) | 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE | non-polymer | 494.6 | 4 | Chemie (CM5) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 491 (UniProt: P00178)
| PDB | External Database | Details |
|---|---|---|
| Lys 29 | Arg 29 | conflict |
| Ser 221 | Pro 221 | conflict |
| Tyr 226 | His 226 | engineered mutation |
| Trp 244 | Phe 244 | engineered mutation |
| His 492 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 111898.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 3211.3 | |
| All* | Total formula weight | 115110.0 |
