7XMS

CryoEM structure of somatostatin receptor 4 (SSTR4) in complex with Gi1 and its endogeneous ligand SST-14

Summary for 7XMS

Entry DOI	10.2210/pdb7xms/pdb
EMDB information	33303
Descriptor	Somatostatin receptor type 4, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total)
Functional Keywords	g protein-coupled receptor, somatostatin receptor 4, cryo-em, structural protein, signaling protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	160866.99
Authors	Wenli, Z.,Shuo, H.,Na, Q.,Wenbo, Z.,Mengjie, L.,Dehua, Y.,Ming-Wei, W.,Wu, B.,Zhao, Q. (deposition date: 2022-04-26, release date: 2022-08-03, Last modification date: 2022-08-17)
Primary citation	Zhao, W.,Han, S.,Qiu, N.,Feng, W.,Lu, M.,Zhang, W.,Wang, M.,Zhou, Q.,Chen, S.,Xu, W.,Du, J.,Chu, X.,Yi, C.,Dai, A.,Hu, L.,Shen, M.Y.,Sun, Y.,Zhang, Q.,Ma, Y.,Zhong, W.,Yang, D.,Wang, M.W.,Wu, B.,Zhao, Q. Structural insights into ligand recognition and selectivity of somatostatin receptors. Cell Res., 32:761-772, 2022 Cited by PubMed: 35739238 DOI: 10.1038/s41422-022-00679-x PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.9 Å)

Structure validation