Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
3E1U
DownloadVisualize
BU of 3e1u by Molmil
The Crystal Structure of the Anti-Viral APOBEC3G Catalytic Domain
分子名称: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION
著者Holden, L, Prochnow, C, Chang, Y.P, Bransteitter, R, Chelico, L, Sen, U, Stevens, R.C, Goodman, R.F, Chen, X.S.
登録日2008-08-04
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications.
Nature, 456, 2008
3ZVW
DownloadVisualize
BU of 3zvw by Molmil
Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3,3-DIMETHYLBUTAN-1-OL, ACETONE, ...
著者Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P.
登録日2011-07-28
公開日2012-02-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein.
J.Am.Chem.Soc., 133, 2011
3ZCZ
DownloadVisualize
BU of 3zcz by Molmil
Crystal structure of a complex between Actinomadura R39 DD-peptidase and a trifluoroketone inhibitor
分子名称: (2R)-2-amino-7-oxo-7-{[(2R,3S)-4,4,4-trifluoro-3-hydroxybutan-2-yl]amino}heptanoic acid, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, ...
著者Sauvage, E, Herman, R, Kerff, F, Rocaboy, M, Charlier, P.
登録日2012-11-23
公開日2013-03-27
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Inhibition of Dd-Peptidases by a Specific Trifluoroketone: Crystal Structure of a Complex with the Actinomadura R39 Dd-Peptidase.
Biochemistry, 52, 2013
5W9D
DownloadVisualize
BU of 5w9d by Molmil
Estrogen Receptor Alpha Ligand Binding Domain C381S, C417S, C530S Mutant in Complex with Endoxifen
分子名称: Endoxifen, Estrogen receptor
著者Fanning, S.W, Greene, G.L.
登録日2017-06-23
公開日2017-10-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.6464 Å)
主引用文献Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer.
Mol. Pharmacol., 94, 2018
4AR0
DownloadVisualize
BU of 4ar0 by Molmil
N0 domain of Neisseria meningitidis Pilus assembly protein PilQ
分子名称: TYPE IV PILUS BIOGENESIS AND COMPETENCE PROTEIN PILQ
著者Phelan, M.M, Berry, J.L, Derrick, J.P, Lian, L.Y.
登録日2012-04-20
公開日2012-10-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure and Assembly of a Trans-Periplasmic Channel for Type Iv Pili in Neisseria Meningitidis.
Plos Pathog., 8, 2012
9GQO
DownloadVisualize
BU of 9gqo by Molmil
Structure of a Ca2+ bound phosphoenzyme intermediate in the inward-to-outward transition of Ca2+-ATPase 1 from Listeria monocytogenes
分子名称: CALCIUM ION, Calcium-transporting ATPase lmo0841, MAGNESIUM ION
著者Hansen, S.B, Flygaard, R.F, Kjaergaard, M, Nissen, P.
登録日2024-09-09
公開日2024-10-16
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Structure of the [Ca]E2P intermediate of Ca 2+ -ATPase 1 from Listeria monocytogenes.
Embo Rep., 26, 2025
5WAM
DownloadVisualize
BU of 5wam by Molmil
Structure of BamE from Neisseria gonorrhoeae
分子名称: Outer membrane protein assembly factor BamE, ZINC ION
著者Korotkov, K.V, Buchanan, S.K, Noinaj, N.
登録日2017-06-26
公開日2017-12-06
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural and functional insights into the role of BamD and BamE within the beta-barrel assembly machinery in Neisseria gonorrhoeae.
J. Biol. Chem., 293, 2018
5WAQ
DownloadVisualize
BU of 5waq by Molmil
Structure of BamD from Neisseria gonorrhoeae
分子名称: Outer membrane protein assembly factor BamD
著者Korotkov, K.V, Buchanan, S.K, Noinaj, N.
登録日2017-06-26
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Structural and functional insights into the role of BamD and BamE within the beta-barrel assembly machinery in Neisseria gonorrhoeae.
J. Biol. Chem., 293, 2018
5WI1
DownloadVisualize
BU of 5wi1 by Molmil
Crystal structure of human NAMPT with fragment 5: (3E)-3-[(phenylamino)methylidene]oxan-2-one
分子名称: (3E)-3-[(phenylamino)methylidene]oxan-2-one, Nicotinamide phosphoribosyltransferase, SULFATE ION
著者Longenecker, K.L, Raich, D, Korepanova, A.V.
登録日2017-07-18
公開日2018-01-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Fragment-based discovery of a potent NAMPT inhibitor.
Bioorg. Med. Chem. Lett., 28, 2018
5W9C
DownloadVisualize
BU of 5w9c by Molmil
Estrogen Receptor Alpha Ligand Binding Domain C381S, C417S, C530S in Complex with 4-hydroxytamoxifen
分子名称: 4-HYDROXYTAMOXIFEN, Estrogen receptor
著者Fanning, S.W, Greene, G.W.
登録日2017-06-23
公開日2018-06-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer.
Mol. Pharmacol., 94, 2018
5VAR
DownloadVisualize
BU of 5var by Molmil
Crystal structure of KDM4A tandem TUDOR domain in complex with a tri-methyl lysine competitive inhibitor
分子名称: (1R,2S,3R,4S)-3-[(dimethylamino)methyl]-1-phenylbicyclo[2.2.1]heptan-2-ol, Lysine-specific demethylase 4A
著者Judge, R.A, Upadhyay, A.K.
登録日2017-03-27
公開日2018-03-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Targeting lysine specific demethylase 4A (KDM4A) tandem TUDOR domain - A fragment based approach.
Bioorg. Med. Chem. Lett., 28, 2018
5W10
DownloadVisualize
BU of 5w10 by Molmil
Lcd1 GAF domain in complex with cAMP ligand
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cGMP-specific phosphodiesterase
著者Guzzo, C.R, Maciel, N.K, Barbosa, A.S, Farah, C.S.
登録日2017-06-01
公開日2017-06-28
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural and Enzymatic Characterization of a cAMP-Dependent Diguanylate Cyclase from Pathogenic Leptospira Species.
J. Mol. Biol., 429, 2017
4AQZ
DownloadVisualize
BU of 4aqz by Molmil
B2 domain of Neisseria meningitidis Pilus assembly protein PilQ
分子名称: TYPE IV PILUS BIOGENESIS AND COMPETENCE PROTEIN PILQ
著者Phelan, M.M, Berry, J.L, Derrick, J.P, Lian, L.Y.
登録日2012-04-20
公開日2012-10-17
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structure and Assembly of a Trans-Periplasmic Channel for Type Iv Pili in Neisseria Meningitidis.
Plos Pathog., 8, 2012
5VO6
DownloadVisualize
BU of 5vo6 by Molmil
CRYSTAL STRUCTURE OF JAK3 KINASE DOMAIN IN COMPLEX WITH A PYRROLOPYRIDAZINE INHIBITOR
分子名称: 4-{[(1R,3S)-3-amino-2,2,3-trimethylcyclopentyl]amino}-6-phenylpyrrolo[1,2-b]pyridazine-3-carboxamide, Tyrosine-protein kinase JAK3
著者Sack, J.S.
登録日2017-05-02
公開日2017-05-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Discovery of potent and efficacious pyrrolopyridazines as dual JAK1/3 inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
8Y2R
DownloadVisualize
BU of 8y2r by Molmil
NMR Solution Structure of the 2:1 Coptisine-ATF4-G4 Complex
分子名称: 6,7-dihydro[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquino[3,2-a]isoquinolin-5-ium, DNA (5'-D(*TP*AP*AP*GP*GP*GP*AP*GP*GP*GP*AP*GP*GP*GP*AP*AP*GP*GP*GP*AP*GP*C*(LIG)*(LIG))-3')
著者Xiao, C.M, Li, Y.P, Liu, Y.S, Dong, R.F, He, X.Y, Lin, Q, Zang, X, Wang, K.B, Xia, Y.Z, Kong, L.Y.
登録日2024-01-27
公開日2024-12-04
最終更新日2025-06-18
実験手法SOLUTION NMR
主引用文献Overcoming Cancer Persister Cells by Stabilizing the ATF4 Promoter G-quadruplex.
Adv Sci, 11, 2024
3ZVT
DownloadVisualize
BU of 3zvt by Molmil
Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein
分子名称: 2,6 DIMETHOXYBENZAMIDOBORONIC ACID, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, ...
著者Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P.
登録日2011-07-27
公開日2012-02-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein.
J.Am.Chem.Soc., 133, 2011
5WI0
DownloadVisualize
BU of 5wi0 by Molmil
Crystal structure of human NAMPT with fragment 2: 2-[(2-fluorophenyl)amino]-6-propylpyrimidin-4(3H)-one
分子名称: 2-[(2-fluorophenyl)amino]-6-propylpyrimidin-4(3H)-one, Nicotinamide phosphoribosyltransferase
著者Longenecker, K.L, Raich, D, Korepanova, A.V.
登録日2017-07-18
公開日2018-01-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Fragment-based discovery of a potent NAMPT inhibitor.
Bioorg. Med. Chem. Lett., 28, 2018
4D9Q
DownloadVisualize
BU of 4d9q by Molmil
Inhibiting Alternative Pathway Complement Activation by Targeting the Exosite on Factor D
分子名称: Anti-Factor D, heavy chain, light chain, ...
著者Murray, J.M, Wiesmann, C.
登録日2012-01-11
公開日2012-02-22
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Inhibiting alternative pathway complement activation by targeting the factor d exosite.
J.Biol.Chem., 287, 2012
4D9R
DownloadVisualize
BU of 4d9r by Molmil
Inhibiting Alternative Pathway Complement Activation by Targeting the Exosite on Factor D
分子名称: CHLORIDE ION, Complement factor D, Fab heavy chain, ...
著者Murray, J.M, Wiesmann, C.
登録日2012-01-11
公開日2012-02-22
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Inhibiting alternative pathway complement activation by targeting the factor d exosite.
J.Biol.Chem., 287, 2012
4XH3
DownloadVisualize
BU of 4xh3 by Molmil
Mechanistic insights into anchorage of the contractile ring from yeast to humans
分子名称: Actin-binding protein anillin
著者Sun, L.F, Guan, R.F, Chen, Z.C.
登録日2015-01-04
公開日2015-07-15
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mechanistic insights into the anchorage of the contractile ring by anillin and mid1
Dev.Cell, 33, 2015
1QV8
DownloadVisualize
BU of 1qv8 by Molmil
B-DNA Dodecamer d(CGCGAATTCGCG)2 complexed with proamine
分子名称: 2'-(4-DIMETHYLAMINOPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'
著者Squire, C.J, Clark, G.R.
登録日2003-08-27
公開日2004-09-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献In vitro studies with methylproamine: a potent new radioprotector.
Cancer Res., 64, 2004
6UE6
DownloadVisualize
BU of 6ue6 by Molmil
PWWP1 domain of NSD2 in complex with MR837
分子名称: 4-cyano-N-cyclopropyl-N-[(thiophen-2-yl)methyl]benzamide, Histone-lysine N-methyltransferase NSD2, UNKNOWN ATOM OR ION
著者Liu, Y, Tempel, W, De Freitas, R.F, Schapira, M, Brown, P.J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC)
登録日2019-09-20
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2.
J.Med.Chem., 64, 2021
1QV4
DownloadVisualize
BU of 1qv4 by Molmil
B-DNA Dodecamer CGTGAATTCACG complexed with minor groove binder methylproamine
分子名称: 2'-(3-METHYL-4-DIMETHYLAMINOPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'
著者Squire, C.J, Clark, G.R.
登録日2003-08-26
公開日2004-09-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献In vitro studies with methylproamine: a potent new radioprotector.
Cancer Res., 64, 2004
1TES
DownloadVisualize
BU of 1tes by Molmil
OXYGEN BINDING MUSCLE PROTEIN
分子名称: METHYLETHYLAMINE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Smith, R.D, Phillips Jr, G.N, Olson, J.S.
登録日1996-05-06
公開日1996-11-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mechanism of NO-induced oxidation of myoglobin and hemoglobin.
Biochemistry, 35, 1996
6OTZ
DownloadVisualize
BU of 6otz by Molmil
Structure of HIV-1 Reverse Transcriptase (RT) in complex with dsDNA and (+)FTC-TP
分子名称: DNA Primer 20-mer, DNA template 27-mer, GLYCEROL, ...
著者Bertoletti, N, Anderson, K.S.
登録日2019-05-03
公開日2019-07-24
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.857 Å)
主引用文献Structural insights into the recognition of nucleoside reverse transcriptase inhibitors by HIV-1 reverse transcriptase: First crystal structures with reverse transcriptase and the active triphosphate forms of lamivudine and emtricitabine.
Protein Sci., 28, 2019

238582

件を2025-07-09に公開中

PDB statisticsPDBj update infoContact PDBjnumon