1QV8

B-DNA Dodecamer d(CGCGAATTCGCG)2 complexed with proamine

Summary for 1QV8

• Entry DOI: 10.2210/pdb1qv8/pdb
• Related: 1QV4
• Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', 2'-(4-DIMETHYLAMINOPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE (3 entities in total)
• Functional Keywords: b-dna, minor groove binder, dna
• Total number of polymer chains: 2
• Total formula weight: 7778.35

Authors

Squire, C.J.,Clark, G.R. (deposition date: 2003-08-27, release date: 2004-09-07, Last modification date: 2024-02-14)

• Primary citation: Martin, R.F.,Broadhurst, S.,Reum, M.E.,Squire, C.J.,Clark, G.R.,Lobachevsky, P.N.,White, J.M.,Clark, C.,Sy, D.,Spotheim-Maurizot, M.,Kelly, D.P.; In vitro studies with methylproamine: a potent new radioprotector.; Cancer Res., 64:1067-1070, 2004; PubMed: 14871839; DOI: 10.1158/0008-5472.CAN-03-2423

Experimental method

X-RAY DIFFRACTION (2.5 Å)