5W10
Lcd1 GAF domain in complex with cAMP ligand
Summary for 5W10
Entry DOI | 10.2210/pdb5w10/pdb |
Descriptor | cGMP-specific phosphodiesterase, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE (3 entities in total) |
Functional Keywords | gaf domain, camp binding domain, effector domain, regulates the dgc activity of the ggdef domain, hydrolase |
Biological source | Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130) |
Total number of polymer chains | 4 |
Total formula weight | 90266.92 |
Authors | Guzzo, C.R.,Maciel, N.K.,Barbosa, A.S.,Farah, C.S. (deposition date: 2017-06-01, release date: 2017-06-28, Last modification date: 2020-01-01) |
Primary citation | da Costa Vasconcelos, F.N.,Maciel, N.K.,Favaro, D.C.,de Oliveira, L.C.,Barbosa, A.S.,Salinas, R.K.,de Souza, R.F.,Farah, C.S.,Guzzo, C.R. Structural and Enzymatic Characterization of a cAMP-Dependent Diguanylate Cyclase from Pathogenic Leptospira Species. J. Mol. Biol., 429:2337-2352, 2017 Cited by PubMed: 28601495DOI: 10.1016/j.jmb.2017.06.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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