5W10

Lcd1 GAF domain in complex with cAMP ligand

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	cGMP-specific phosphodiesterase	polymer	195	22237.5	4	UniProt (Q72MQ6) Pfam (PF01590)	Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)
2	E, F, G, H (A, B, C, D)	ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE	non-polymer		329.2	4	Chemie (CMP)
3	I, J, K, L (A, B, C, D)	water	water		18.0	346	Chemie (HOH)

Sequence modifications

A, B, C, D: 2 - 175 (UniProt: Q72MQ6)

PDB	External Database	Details
Mse -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Mse 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	88950.1
Non-Polymers*	Number of molecules	4
	Total formula weight	1316.8
All*	Total formula weight	90266.9

*Water molecules are not included.