6BV7
 
 | |
4DVB
 | | The crystal structure of the Fab fragment of pro-uPA antibody mAb-112 | | 分子名称: | Fab fragment of pro-uPA antibody mAb-112, SULFATE ION, TETRAETHYLENE GLYCOL | | 著者 | Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M. | | 登録日 | 2012-02-23 | | 公開日 | 2013-01-16 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Rezymogenation of active urokinase induced by an inhibitory antibody.
Biochem.J., 449, 2013
|
|
4DVA
 | | The crystal structure of human urokinase-type plasminogen activator catalytic domain | | 分子名称: | HEXAETHYLENE GLYCOL, SULFATE ION, Urokinase-type plasminogen activator | | 著者 | Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M. | | 登録日 | 2012-02-23 | | 公開日 | 2013-01-16 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Rezymogenation of active urokinase induced by an inhibitory antibody
Biochem.J., 449, 2013
|
|
4XSK
 | | Structure of PAItrap, an uPA mutant | | 分子名称: | GLYCEROL, SULFATE ION, TRIETHYLENE GLYCOL, ... | | 著者 | Gong, L, Proulle, V, Hong, Z, Lin, Z, Liu, M, Yuan, C, Lin, L, Furie, B, Flaumenhaft, R, Andreasen, P, Furie, B, Huang, M. | | 登録日 | 2015-01-22 | | 公開日 | 2016-02-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of PAItrap, an uPA mutant
To Be Published
|
|
6XVD
 | | Crystal structure of complex of urokinase and a upain-1 variant(W3F) in pH7.4 condition | | 分子名称: | Urokinase-type plasminogen activator, upain-1-W3F | | 著者 | Xue, G.P, Xie, X, Zhou, Y, Yuan, C, Huang, M.D, Jiang, L.G. | | 登録日 | 2020-01-21 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Insight to the residue in P2 position prevents the peptide inhibitor from being hydrolyzed by serine proteases.
Biosci.Biotechnol.Biochem., 84, 2020
|
|
3G7N
 | | Crystal Structure of a Triacylglycerol Lipase from Penicillium Expansum at 1.3 | | 分子名称: | DI(HYDROXYETHYL)ETHER, Lipase, PENTAETHYLENE GLYCOL, ... | | 著者 | Bian, C.B, Yuan, C, Chen, L.Q, Edward, J.M, Lin, L, Jiang, L.G, Huang, Z.X, Huang, M.D. | | 登録日 | 2009-02-10 | | 公開日 | 2010-02-23 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Crystal structure of a triacylglycerol lipase from Penicillium expansum at 1.3 A determined by sulfur SAD
Proteins, 78, 2010
|
|
8Y7F
 | |
8Y7G
 | | Crystal structure of the Marinitoga sp. Csx1-Crn2 H495A mutant in complex with cyclic-tetraadenylate (cA4) | | 分子名称: | ACETATE ION, CRISPR-associated protein, RNA (5'-R(P*AP*A)-3'), ... | | 著者 | Zhang, D, Yuan, C, Lin, Z. | | 登録日 | 2024-02-04 | | 公開日 | 2024-07-17 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Structural insight into the Csx1-Crn2 fusion self-limiting ribonuclease of type III CRISPR system.
Nucleic Acids Res., 52, 2024
|
|
8Y6Z
 | |
8Y75
 | |
2FA9
 | | The crystal structure of Sar1[H79G]-GDP provides insight into the coat-controlled GTP hydrolysis in the disassembly of COP II | | 分子名称: | GTP-binding protein SAR1b, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Rao, Y, Huang, M, Yuan, C, Bian, C, Hou, X. | | 登録日 | 2005-12-07 | | 公開日 | 2006-09-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of Sar1[H79G]-GDP Which Provides Insight into the Coat-controlled GTP Hydrolysis in the Disassembly of COP II
Chin.J.Struct.Chem., 25, 2006
|
|
2FMX
 | | An open conformation of switch I revealed by Sar1-GDP crystal structure at low Mg(2+) | | 分子名称: | GTP-binding protein SAR1b, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Rao, Y, Bian, C, Yuan, C, Li, Y, Huang, M. | | 登録日 | 2006-01-10 | | 公開日 | 2006-09-05 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | An open conformation of switch I revealed by Sar1-GDP crystal structure at low Mg(2+)
Biochem.Biophys.Res.Commun., 348, 2006
|
|
4QTH
 | | Crystal structure of anti-uPAR Fab 8B12 | | 分子名称: | anti-uPAR antibody, heavy chain, light chain | | 著者 | Zhao, B, Yuan, C, Luo, Z, Huang, M. | | 登録日 | 2014-07-08 | | 公開日 | 2015-02-25 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation.
J.Mol.Biol., 427, 2015
|
|
4QTI
 | | Crystal structure of human uPAR in complex with anti-uPAR Fab 8B12 | | 分子名称: | Urokinase plasminogen activator surface receptor, anti-uPAR antibody, heavy chain, ... | | 著者 | Zhao, B, Yuan, C, Luo, Z, Huang, M. | | 登録日 | 2014-07-08 | | 公開日 | 2015-02-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation.
J.Mol.Biol., 427, 2015
|
|
3HNY
 | |
3HNB
 | |
3HOB
 | |
4DW2
 | | The crystal structure of uPA in complex with the Fab fragment of mAb-112 | | 分子名称: | Fab fragment of pro-uPA antibody mAb-112, SULFATE ION, Urokinase-type plasminogen activator | | 著者 | Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M. | | 登録日 | 2012-02-24 | | 公開日 | 2013-01-16 | | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | | 主引用文献 | Rezymogenation of active urokinase induced by an inhibitory antibody.
Biochem.J., 449, 2013
|
|
4H42
 | | Synthesis of a Weak Basic uPA Inhibitor and Crystal Structure of Complex with uPA | | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, N-[(2-amino-1,3-benzothiazol-6-yl)carbonyl]glycine, Urokinase-type plasminogen activator | | 著者 | Yu, H.-Y, Gao, D, Zhang, X, Jiang, L.-G, Hong, Z.-B, Yuan, C, Fang, X, Wang, J.-D, Huang, M.-D. | | 登録日 | 2012-09-14 | | 公開日 | 2013-10-30 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Synthesis of a Weak Basic uPA Inhibitor and Crystal Structure of Complex with uPA
CHIN.J.STRUCT.CHEM., 32, 2013
|
|
2JXJ
 | |
2N9C
 | | NRAS Isoform 5 | | 分子名称: | GTPase NRas | | 著者 | Markowitz, J, Mal, T.K, Yuan, C, Courtney, N.B, Patel, M, Stiff, A.R, Blachly, J, Walker, C, Eisfeld, A, de la Chapelle, A, Carson III, W.E. | | 登録日 | 2015-11-13 | | 公開日 | 2016-03-23 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural characterization of NRAS isoform 5.
Protein Sci., 25, 2016
|
|
3TKZ
 | | Structure of the SHP-2 N-SH2 domain in a 1:2 complex with RVIpYFVPLNR peptide | | 分子名称: | PROTEIN (RVIpYFVPLNR peptide), Tyrosine-protein phosphatase non-receptor type 11 | | 著者 | Zhang, Y, Zhang, J, Yuan, C, Hard, R.L, Park, I.H, Li, C, Bell, C.E, Pei, D. | | 登録日 | 2011-08-29 | | 公開日 | 2011-10-26 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain.
Biochemistry, 50, 2011
|
|
3TL0
 | | Structure of SHP2 N-SH2 domain in complex with RLNpYAQLWHR peptide | | 分子名称: | RLNpYAQLWHR peptide, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 11 | | 著者 | Zhang, Y, Zhang, J, Yuan, C, Hard, R.L, Park, I.H, Li, C, Bell, C.E, Pei, D. | | 登録日 | 2011-08-29 | | 公開日 | 2011-09-28 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain.
Biochemistry, 50, 2011
|
|
3M61
 | | Crystal structure of complex of urokinase and a upain-1 variant(W3A) in pH4.6 condition | | 分子名称: | Urokinase-type plasminogen activator, upain-1 W3A | | 著者 | Jiang, L, Yuan, C, Wind, T, Andreasen, P.A, Chen, L, Meehan, E.J, Huang, M. | | 登録日 | 2010-03-15 | | 公開日 | 2010-04-07 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Crystal structure of complex of urokinase and a upain-1 variant(W3A) in pH4.6 condition
TO BE PUBLISHED
|
|
3MWI
 | | The complex crystal Structure of Urokianse and 5-nitro-1H-indole-2-amidine | | 分子名称: | 5-nitro-1H-indole-2-carboximidamide, SULFATE ION, Urokinase-type plasminogen activator | | 著者 | Jiang, L.G, Yu, H.Y, Yuan, C, Huang, Z.X, Huang, M.D. | | 登録日 | 2010-05-06 | | 公開日 | 2011-06-01 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | The complex crystal Structure of Urokianse and 5-nitro-1H-indole-2-amidine
To be Published
|
|
