5VO8
 
 | | X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter | | 分子名称: | DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*CP*TP*GP*AP*TP*GP*CP*AP*CP*C)-3'), DNA (5'-D(P*GP*GP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Murakami, K.S, Shin, Y, Turnbough Jr, C.L, Molodtsov, V. | | 登録日 | 2017-05-02 | | 公開日 | 2017-05-24 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | X-ray crystal structure of a reiterative transcription complex reveals an atypical RNA extension pathway.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5VOI
 | | X-ray crystal structure of bacterial RNA polymerase and pyrG promoter complex | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Murakami, K.S, Shin, Y, Turnbough Jr, C.L, Molodtsov, V. | | 登録日 | 2017-05-02 | | 公開日 | 2017-05-24 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | X-ray crystal structure of a reiterative transcription complex reveals an atypical RNA extension pathway.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4GVJ
 | | Tyk2 (JH1) in complex with adenosine di-phosphate | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Non-receptor tyrosine-protein kinase TYK2 | | 著者 | Liang, J, Abbema, A.V, Bao, L, Barrett, K, Beresini, M, Berezhkovskiy, L, Blair, W, Chang, C, Driscoll, J, Eigenbrot, C, Ghilardi, N, Gibbons, P, Halladay, J, Johnson, A, Kohli, P.B, Lai, Y, Liimatta, M, Mantik, P, Menghrajani, K, Murray, J, Sambrone, A, Shao, Y, Shia, S, Shin, Y, Smith, J, Sohn, S, Stanley, M, Tsui, V, Ultsch, M, Wu, L, Zhang, B, Magnuson, S. | | 登録日 | 2012-08-30 | | 公開日 | 2013-08-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Lead identification of novel and selective TYK2 inhibitors.
Eur.J.Med.Chem., 67, 2013
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7XMA
 | | Crystal structure of Bovine heart cytochrome c oxidase, apo structure with DMSO | | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... | | 著者 | Nishida, Y, Shinzawa-Itoh, K, Mizuno, N, Kumasaka, T, Yoshikawa, S, Tsukihara, T, Takashima, S, Shintani, Y. | | 登録日 | 2022-04-25 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases.
Nat Commun, 13, 2022
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7XMB
 | | Crystal structure of Bovine heart cytochrome c oxidase, the structure complexed with an allosteric inhibitor T113 | | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... | | 著者 | Nishida, Y, Shinzawa-Itoh, K, Mizuno, N, Kumasaka, T, Yoshikawa, S, Tsukihara, T, Shintani, Y, Takashima, S. | | 登録日 | 2022-04-25 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases.
Nat Commun, 13, 2022
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7XMC
 | | Cryo-EM structure of Cytochrome bo3 from Escherichia coli, apo structure with DMSO | | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ... | | 著者 | Nishida, Y, Shigematsu, H, Iwamoto, T, Takashima, S, Shintani, Y. | | 登録日 | 2022-04-25 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases.
Nat Commun, 13, 2022
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7XMD
 | | Cryo-EM structure of Cytochrome bo3 from Escherichia coli, the structure complexed with an allosteric inhibitor N4 | | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ... | | 著者 | Nishida, Y, Shigematsu, H, Iwamoto, T, Takashima, S, Shintani, Y. | | 登録日 | 2022-04-25 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | | 主引用文献 | Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases.
Nat Commun, 13, 2022
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1IQP
 | | Crystal Structure of the Clamp Loader Small Subunit from Pyrococcus furiosus | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, RFCS | | 著者 | Oyama, T, Ishino, Y, Cann, I.K.O, Ishino, S, Morikawa, K. | | 登録日 | 2001-07-24 | | 公開日 | 2001-09-19 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Atomic Structure of the Clamp Loader Small Subunit from Pyrococcus furiosus
Mol.Cell, 8, 2001
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6Z1M
 | | Structure of an Ancestral glycosidase (family 1) bound to heme | | 分子名称: | 1,2-ETHANEDIOL, Ancestral reconstructed glycosidase, GLYCEROL, ... | | 著者 | Gavira, J.A, Risso, V.A, Sanchez-Ruiz, J.M, Gamiz-Arco, G, Gutierrez-Rus, L, Ibarra-Molero, B, Oshino, Y, Petrovic, D, Romero-Rivera, A, Seelig, B, Kamerlin, S.C.L, Gaucher, E.A. | | 登録日 | 2020-05-14 | | 公開日 | 2020-07-22 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Heme-binding enables allosteric modulation in an ancient TIM-barrel glycosidase.
Nat Commun, 12, 2021
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6Z1H
 | | Ancestral glycosidase (family 1) | | 分子名称: | ANCESTRAL RECONSTRUCTED GLYCOSIDASE, GLYCEROL, ISOPROPYL ALCOHOL, ... | | 著者 | Gavira, J.A, Risso, V.A, Sanchez-Ruiz, J.M, Gamiz-Arco, G, Gutierrez-Rus, L, Ibarra-Molero, B, Hoshino, Y, Petrovic, D, Romero-Rivera, A, Seelig, B, Kamerlin, S.C.L, Gaucher, E.A. | | 登録日 | 2020-05-13 | | 公開日 | 2020-07-22 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Heme-binding enables allosteric modulation in an ancient TIM-barrel glycosidase.
Nat Commun, 12, 2021
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1IPI
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1WP9
 | | Crystal structure of Pyrococcus furiosus Hef helicase domain | | 分子名称: | ATP-dependent RNA helicase, putative, PHOSPHATE ION | | 著者 | Nishino, T, Komori, K, Tsuchiya, D, Ishino, Y, Morikawa, K. | | 登録日 | 2004-08-31 | | 公開日 | 2005-02-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal Structure and Functional Implications of Pyrococcus furiosus Hef Helicase Domain Involved in Branched DNA Processing
Structure, 13, 2005
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1X2I
 | | Crystal Structure Of Archaeal Xpf/Mus81 Homolog, Hef From Pyrococcus Furiosus, Helix-hairpin-helix Domain | | 分子名称: | Hef helicase/nuclease | | 著者 | Nishino, T, Komori, K, Ishino, Y, Morikawa, K. | | 登録日 | 2005-04-24 | | 公開日 | 2005-09-13 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structural and Functional Analyses of an Archaeal XPF/Rad1/Mus81 Nuclease: Asymmetric DNA Binding and Cleavage Mechanisms
STRUCTURE, 13, 2005
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1AN9
 | | D-AMINO ACID OXIDASE COMPLEX WITH O-AMINOBENZOATE | | 分子名称: | 2-AMINOBENZOIC ACID, D-AMINO ACID OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Miura, R, Setoyama, C, Nishina, Y, Shiga, K, Mizutani, H, Miyahara, I, Hirotsu, K. | | 登録日 | 1997-06-28 | | 公開日 | 1997-11-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural and mechanistic studies on D-amino acid oxidase x substrate complex: implications of the crystal structure of enzyme x substrate analog complex.
J.Biochem.(Tokyo), 122, 1997
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1GEF
 | | Crystal structure of the archaeal holliday junction resolvase HJC | | 分子名称: | HOLLIDAY JUNCTION RESOLVASE, SULFATE ION | | 著者 | Nishino, T, Komori, K, Tsuchiya, D, Ishino, Y, Morikawa, K. | | 登録日 | 2000-11-08 | | 公開日 | 2001-03-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the archaeal holliday junction resolvase Hjc and implications for DNA recognition.
Structure, 9, 2001
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1IZ4
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1J23
 | | Crystal structure of archaeal XPF/Mus81 homolog, Hef from Pyrococcus furiosus, nuclease domain | | 分子名称: | ATP-dependent RNA helicase, putative | | 著者 | Nishino, T, Komori, K, Ishino, Y, Morikawa, K. | | 登録日 | 2002-12-25 | | 公開日 | 2003-04-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | X-Ray and Biochemical Anatomy of an Archaeal XPF/Rad1/Mus81 Family Nuclease. Similarity between Its Endonuclease Domain and Restriction Enzymes
Structure, 11, 2003
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1J25
 | | Crystal structure of archaeal XPF/Mus81 homolog, Hef from Pyrococcus furiosus, nuclease domain, Mn cocrystal | | 分子名称: | ATP-dependent RNA helicase, putative, MANGANESE (II) ION | | 著者 | Nishino, T, Komori, K, Ishino, Y, Morikawa, K. | | 登録日 | 2002-12-25 | | 公開日 | 2003-04-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | X-Ray and Biochemical Anatomy of an Archaeal XPF/Rad1/Mus81 Family Nuclease. Similarity between Its Endonuclease Domain and Restriction Enzymes
Structure, 11, 2003
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1J22
 | | Crystal structure of archaeal XPF/Mus81 homolog, Hef from Pyrococcus furiosus, nuclease domain, selenomet derivative | | 分子名称: | ATP-dependent RNA helicase, putative | | 著者 | Nishino, T, Komori, K, Ishino, Y, Morikawa, K. | | 登録日 | 2002-12-25 | | 公開日 | 2003-04-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | X-Ray and Biochemical Anatomy of an Archaeal XPF/Rad1/Mus81 Family Nuclease. Similarity between Its Endonuclease Domain and Restriction Enzymes
Structure, 11, 2003
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1ISQ
 | | Pyrococcus furiosus PCNA complexed with RFCL PIP-box peptide | | 分子名称: | Proliferating Cell Nuclear Antigen, replication factor C large subunit | | 著者 | Matsumiya, S, Ishino, S, Ishino, Y, Morikawa, K. | | 登録日 | 2001-12-19 | | 公開日 | 2002-10-23 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Physical interaction between proliferating cell nuclear antigen and
replication factor C from Pyrococcus furiosus
Genes Cells, 7, 2002
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1IZ5
 | | Pyrococcus furiosus PCNA mutant (Met73Leu, Asp143Ala, Asp147Ala): orthorhombic form | | 分子名称: | Proliferating cell nuclear antigen | | 著者 | Matsumiya, S, Ishino, S, Ishino, Y, Morikawa, K. | | 登録日 | 2002-09-23 | | 公開日 | 2003-04-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Intermolecular ion pairs maintain the toroidal structure of Pyrococcus furiosus PCNA
PROTEIN SCI., 12, 2003
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1J24
 | | Crystal structure of archaeal XPF/Mus81 homolog, Hef from Pyrococcus furiosus, nuclease domain, Ca cocrystal | | 分子名称: | ATP-dependent RNA helicase, putative, CALCIUM ION | | 著者 | Nishino, T, Komori, K, Ishino, Y, Morikawa, K. | | 登録日 | 2002-12-25 | | 公開日 | 2003-04-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | X-Ray and Biochemical Anatomy of an Archaeal XPF/Rad1/Mus81 Family Nuclease. Similarity between Its Endonuclease Domain and Restriction Enzymes
Structure, 11, 2003
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7COY
 | | Structure of the far-red light utilizing photosystem I of Acaryochloris marina | | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, CHLOROPHYLL D, ... | | 著者 | Kawakami, K, Yonekura, K, Hamaguchi, T, Kashino, Y, Shinzawa-Itoh, K, Inoue-Kashino, N, Itoh, S, Ifuku, K, Yamashita, E. | | 登録日 | 2020-08-05 | | 公開日 | 2021-03-31 | | 最終更新日 | 2021-05-05 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Structure of the far-red light utilizing photosystem I of Acaryochloris marina.
Nat Commun, 12, 2021
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5GKI
 | | Structure of EndoMS-dsDNA3 complex | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*GP*CP*CP*TP*AP*GP*GP*TP*CP*CP*CP*GP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*CP*GP*GP*GP*GP*CP*CP*TP*AP*GP*GP*C)-3'), ... | | 著者 | Nakae, S, Hijikata, A, Tsuji, T, Yonezawa, K, Kouyama, K, Mayanagi, K, Ishino, S, Ishino, Y, Shirai, T. | | 登録日 | 2016-07-04 | | 公開日 | 2016-11-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of the EndoMS-DNA Complex as Mismatch Restriction Endonuclease
Structure, 24, 2016
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5GKJ
 | | Structure of EndoMS in apo form | | 分子名称: | Endonuclease EndoMS | | 著者 | Nakae, S, Hijikata, A, Tsuji, T, Yonezawa, K, Kouyama, K, Mayanagi, K, Ishino, S, Ishino, Y, Shirai, T. | | 登録日 | 2016-07-04 | | 公開日 | 2016-11-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structure of the EndoMS-DNA Complex as Mismatch Restriction Endonuclease
Structure, 24, 2016
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