4XX8
 
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8SPN
 | | Crystal structure of macrophage migration inhibitory factor in complex with T614 | | 分子名称: | GLYCEROL, ISOPROPYL ALCOHOL, Iguratimod, ... | | 著者 | Pantouris, G, Lolis, E. | | 登録日 | 2023-05-03 | | 公開日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Iguratimod, an allosteric inhibitor of macrophage migration inhibitory factor (MIF), prevents mortality and oxidative stress in a murine model of acetaminophen overdose.
Mol Med, 30, 2024
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3DJI
 | | Crystal Structure of Macrophage Migration Inhibitory Factor Bound to an Acetaminophen Dimer Derived from NAPQI | | 分子名称: | CHLORIDE ION, Macrophage migration inhibitory factor, N,N'-(6,6'-dihydroxybiphenyl-3,3'-diyl)diacetamide | | 著者 | Crichlow, G.V, Lolis, E. | | 登録日 | 2008-06-23 | | 公開日 | 2008-12-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural and kinetic analyses of macrophage migration inhibitory factor active site interactions.
Biochemistry, 48, 2009
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3GV3
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6BG7
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6BG6
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8TT9
 | | X-ray structure of Macrophage Migration Inhibitory Factor (MIF) Covalently Bound to 4-hydroxyphenylpyruvate (HPP) | | 分子名称: | 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor | | 著者 | Schroder, G.C, Meilleur, F, Nix, J.C, Crichlow, G.V, Lolis, E.J. | | 登録日 | 2023-08-13 | | 公開日 | 2024-08-28 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | X-ray structure of Macrophage Migration Inhibitory Factor (MIF) Covalently Bound to 4-hydroxyphenylpyruvate (HPP)
To Be Published
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6OYB
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6OYE
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6OYG
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6OY8
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3KER
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3KAN
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3HP3
 | | Crystal structure of CXCL12 | | 分子名称: | CXCL12 protein, GOLD ION | | 著者 | Murphy, J.W, Lolis, E, Xiong, Y, Yuan, H, Crichlow, G. | | 登録日 | 2009-06-03 | | 公開日 | 2010-01-26 | | 最終更新日 | 2018-05-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Heterologous quaternary structure of CXCL12 and its relationship to the CC chemokine family
Proteins, 78, 2009
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5UZY
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5UMJ
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5UMK
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3CE4
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4P0H
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5BSC
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5BSI
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5BS9
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7MRU
 | | Crystal structure of S62A MIF2 mutant | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, D-dopachrome decarboxylase | | 著者 | Murphy, E.L, Manjula, R, Murphy, J.W, Lolis, E. | | 登録日 | 2021-05-09 | | 公開日 | 2021-08-18 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | | 主引用文献 | A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase.
J.Biol.Chem., 297, 2021
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7MSE
 | | High-resolution crystal structure of hMIF2 with tartrate at the active site | | 分子名称: | D-dopachrome decarboxylase, L(+)-TARTARIC ACID | | 著者 | Murphy, E.L, Manjula, R, Murphy, J.W, Lolis, E. | | 登録日 | 2021-05-11 | | 公開日 | 2021-08-18 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | | 主引用文献 | A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase.
J.Biol.Chem., 297, 2021
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7MRV
 | | F100A mutant structure of MIF2 (D-DT) | | 分子名称: | D-dopachrome decarboxylase, SULFATE ION | | 著者 | Murphy, E.L, Manjula, R, Murphy, J.W, Lolis, E. | | 登録日 | 2021-05-09 | | 公開日 | 2021-08-18 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase.
J.Biol.Chem., 297, 2021
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