6OYE

Crystal structure of Y99F mutant of human macrophage migration inhibitory factor

Summary for 6OYE

Entry DOI	10.2210/pdb6oye/pdb
Descriptor	Macrophage migration inhibitory factor, GLYCEROL, SULFATE ION, ... (5 entities in total)
Functional Keywords	isomerase, trimeric, mutation
Biological source	Homo sapiens (Human)
Total number of polymer chains	3
Total formula weight	37914.11
Authors	Pantouris, G.,Lolis, E. (deposition date: 2019-05-14, release date: 2020-04-29, Last modification date: 2023-10-11)
Primary citation	Pantouris, G.,Khurana, L.,Ma, A.,Skeens, E.,Reiss, K.,Batista, V.S.,Lisi, G.P.,Lolis, E.J. Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel. Cell Chem Biol, 27:740-750.e5, 2020 Cited by PubMed: 32433911 DOI: 10.1016/j.chembiol.2020.05.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.53 Å)

Structure validation