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8TT9

X-ray structure of Macrophage Migration Inhibitory Factor (MIF) Covalently Bound to 4-hydroxyphenylpyruvate (HPP)

Summary for 8TT9
Entry DOI10.2210/pdb8tt9/pdb
DescriptorMacrophage migration inhibitory factor, 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, ISOPROPYL ALCOHOL, ... (4 entities in total)
Functional Keywordsmacrophage migration inhibitory factor, cytokine
Biological sourceHomo sapiens (human)
Total number of polymer chains3
Total formula weight37725.83
Authors
Schroder, G.C.,Meilleur, F.,Nix, J.C.,Crichlow, G.V.,Lolis, E.J. (deposition date: 2023-08-13, release date: 2024-08-28, Last modification date: 2025-06-18)
Primary citationSchroder, G.C.,Crichlow, G.V.,Zambrzycka, E.,Pantouris, G.,Nix, J.C.,Chayen, N.,Meilleur, F.,Lolis, E.
X-ray structure of Macrophage Migration Inhibitory Factor (MIF) Covalently Bound to 4-hydroxyphenylpyruvate (HPP)
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.68 Å)
Structure validation

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