8TT9
X-ray structure of Macrophage Migration Inhibitory Factor (MIF) Covalently Bound to 4-hydroxyphenylpyruvate (HPP)
Functional Information from PROSITE/UniProt
| site_id | PS01158 |
| Number of Residues | 15 |
| Details | MIF Macrophage migration inhibitory factor family signature. EPCAlcsLhSIGkIG |
| Chain | Residue | Details |
| A | GLU54-GLY68 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Proton acceptor; via imino nitrogen => ECO:0000250|UniProtKB:P34884 |
| Chain | Residue | Details |
| A | PRO1 | |
| B | PRO1 | |
| C | PRO1 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11170644, ECO:0000269|PubMed:17526494, ECO:0000269|PubMed:19090677 |
| Chain | Residue | Details |
| A | LYS32 | |
| A | ILE64 | |
| A | ASN97 | |
| B | LYS32 | |
| B | ILE64 | |
| B | ASN97 | |
| C | LYS32 | |
| C | ILE64 | |
| C | ASN97 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P34884 |
| Chain | Residue | Details |
| A | LYS77 | |
| B | LYS77 | |
| C | LYS77 |
