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8TT9

X-ray structure of Macrophage Migration Inhibitory Factor (MIF) Covalently Bound to 4-hydroxyphenylpyruvate (HPP)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Macrophage migration inhibitory factorpolymer11412355.13UniProt (P14174)
Pfam (PF01187)
Homo sapiens (human)MIF,Glycosylation-inhibiting factor,GIF,L-dopachrome isomerase,L-dopachrome tautomerase,Phenylpyruvate tautomerase
2D, G, H
(A, B, C)
3-(4-HYDROXY-PHENYL)PYRUVIC ACIDnon-polymer180.23Chemie (ENO)
3E, F
(A)
ISOPROPYL ALCOHOLnon-polymer60.12Chemie (IPA)
4I, J, K
(A, B, C)
waterwater18.0174Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight37065.2
Non-Polymers*Number of molecules5
Total formula weight660.7
All*Total formula weight37725.8
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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