7MSE
High-resolution crystal structure of hMIF2 with tartrate at the active site
Summary for 7MSE
Entry DOI | 10.2210/pdb7mse/pdb |
Descriptor | D-dopachrome decarboxylase, L(+)-TARTARIC ACID (3 entities in total) |
Functional Keywords | cytokine |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 38230.84 |
Authors | Murphy, E.L.,Manjula, R.,Murphy, J.W.,Lolis, E. (deposition date: 2021-05-11, release date: 2021-08-18, Last modification date: 2023-10-18) |
Primary citation | Chen, E.,Reiss, K.,Shah, D.,Manjula, R.,Allen, B.,Murphy, E.L.,Murphy, J.W.,Batista, V.S.,Bhandari, V.,Lolis, E.J.,Lisi, G.P. A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase. J.Biol.Chem., 297:101061-101061, 2021 Cited by PubMed: 34384784DOI: 10.1016/j.jbc.2021.101061 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.27 Å) |
Structure validation
Download full validation report