7MRU
Crystal structure of S62A MIF2 mutant
Summary for 7MRU
| Entry DOI | 10.2210/pdb7mru/pdb |
| Descriptor | D-dopachrome decarboxylase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL (3 entities in total) |
| Functional Keywords | cytokine |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 3 |
| Total formula weight | 37854.72 |
| Authors | Murphy, E.L.,Manjula, R.,Murphy, J.W.,Lolis, E. (deposition date: 2021-05-09, release date: 2021-08-18, Last modification date: 2023-10-18) |
| Primary citation | Chen, E.,Reiss, K.,Shah, D.,Manjula, R.,Allen, B.,Murphy, E.L.,Murphy, J.W.,Batista, V.S.,Bhandari, V.,Lolis, E.J.,Lisi, G.P. A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase. J.Biol.Chem., 297:101061-101061, 2021 Cited by PubMed: 34384784DOI: 10.1016/j.jbc.2021.101061 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.33 Å) |
Structure validation
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