3CE4

Structure of Macrophage Migration Inhibitory Factor Covalently Inhibited by PMSF Treatment

Summary for 3CE4

Entry DOI	10.2210/pdb3ce4/pdb
Descriptor	Macrophage migration inhibitory factor, SULFATE ION, phenylmethanesulfonic acid, ... (6 entities in total)
Functional Keywords	covalent modification, covalent inhibition, cytokine, inflammatory response, isomerase, phosphoprotein
Biological source	Homo sapiens (Human)
Cellular location	Secreted : P14174
Total number of polymer chains	3
Total formula weight	38458.56
Authors	Crichlow, G.V.,Lolis, E. (deposition date: 2008-02-28, release date: 2008-12-30, Last modification date: 2023-08-30)
Primary citation	Crichlow, G.V.,Lubetsky, J.B.,Leng, L.,Bucala, R.,Lolis, E.J. Structural and kinetic analyses of macrophage migration inhibitory factor active site interactions. Biochemistry, 48:132-139, 2009 Cited by PubMed: 19090677 DOI: 10.1021/bi8014423 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation